{"id":{"repo_id":"creighton","oai_identifier":"oai:cdr.creighton.edu:10504/115914"},"canonical_url":"https://search.dev.ndltd.org/etd/creighton/oai:cdr.creighton.edu:10504/115914","repository":{"repo_id":"creighton","name":"Creighton University","base_url":"https://cdr.creighton.edu/server/oai/request"},"display":{"title":"L.E. Factor Test in Acute Disseminated Lupus Erythematosus","abstract":"Systemic lupus erythematosus is a rare disease. And like other rare diseases it becomes scarcer through lack of consideration. Therefore a high index of suspicion is necessary if the diagnosis is to be made more frequently. Before the discovery of a new diagnostic test, acute disseminated lupus erythematosus was a medical curiosity. A few years ago the diagnosis was made with certainty only when the classical picture was encountered. A few astute physicians made the diagnosis in obscure cases but always with some hesitancy. A typical cell was discovered which is diagnostic of the disease and an entity once obscure assumed prominence in medical literature. The profession became more conscious of the disease because with a laboratory procedure there was more confidence in the diagnosis. The realization that the diagnosis has frequently been missed is becoming apparent with the utilization of diagnostic laboratory procedures. | In January 1948, Hargraves, Richmond and Morton announced the discovery of a new cell in bone marrow preparations of patients with acute disseminated lupus erythematosus. Hargraves gave the name L.E. cell to this new entity. A chain of investigations has evolved a new diagnostic procedure for this disease. Lupus erythematosus is now prominent in medical literature and is the subject of a great deal of study. Reports concerning the specificity of this cell for systemic lupus erythematosus are appearing in the literature.","abstract_html":"Systemic lupus erythematosus is a rare disease. And like other rare diseases it becomes scarcer through lack of consideration. Therefore a high index of suspicion is necessary if the diagnosis is to be made more frequently. Before the discovery of a new diagnostic test, acute disseminated lupus erythematosus was a medical curiosity. A few years ago the diagnosis was made with certainty only when the classical picture was encountered. A few astute physicians made the diagnosis in obscure cases but always with some hesitancy. A typical cell was discovered which is diagnostic of the disease and an entity once obscure assumed prominence in medical literature. The profession became more conscious of the disease because with a laboratory procedure there was more confidence in the diagnosis. The realization that the diagnosis has frequently been missed is becoming apparent with the utilization of diagnostic laboratory procedures. | In January 1948, Hargraves, Richmond and Morton announced the discovery of a new cell in bone marrow preparations of patients with acute disseminated lupus erythematosus. Hargraves gave the name L.E. cell to this new entity. A chain of investigations has evolved a new diagnostic procedure for this disease. Lupus erythematosus is now prominent in medical literature and is the subject of a great deal of study. Reports concerning the specificity of this cell for systemic lupus erythematosus are appearing in the literature.","abstract_has_math":false,"creators":["Walsh, John Richard"],"institution":"Creighton University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Howard, M.E."],"committee_chairs":[],"committee_members":[],"year":1951,"date_issued":"1951","date_published":"1951","updated_at":"2026-07-24T01:52:03Z","subjects":[],"languages":["en_US"],"rights":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10504/115914","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Howard, M.E."]},{"key":"dc:creator","label":"Author","values":["Walsh, John Richard"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2018-01-23T19:16:54Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2018-01-23T19:16:54Z"]},{"key":"dc:date.issued","label":"Date","values":["1951"]},{"key":"dc:publisher","label":"Institution","values":["Creighton University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_US"]},{"key":"dc:rights","label":"Dc Rights","values":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10504/115914"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Systemic lupus erythematosus is a rare disease. And like other rare diseases it becomes scarcer through lack of consideration. Therefore a high index of suspicion is necessary if the diagnosis is to be made more frequently. Before the discovery of a new diagnostic test, acute disseminated lupus erythematosus was a medical curiosity. A few years ago the diagnosis was made with certainty only when the classical picture was encountered. A few astute physicians made the diagnosis in obscure cases but always with some hesitancy. A typical cell was discovered which is diagnostic of the disease and an entity once obscure assumed prominence in medical literature. The profession became more conscious of the disease because with a laboratory procedure there was more confidence in the diagnosis. The realization that the diagnosis has frequently been missed is becoming apparent with the utilization of diagnostic laboratory procedures. | In January 1948, Hargraves, Richmond and Morton announced the discovery of a new cell in bone marrow preparations of patients with acute disseminated lupus erythematosus. Hargraves gave the name L.E. cell to this new entity. A chain of investigations has evolved a new diagnostic procedure for this disease. Lupus erythematosus is now prominent in medical literature and is the subject of a great deal of study. Reports concerning the specificity of this cell for systemic lupus erythematosus are appearing in the literature."]},{"key":"dc:title","label":"Title","values":["L.E. Factor Test in Acute Disseminated Lupus Erythematosus"]}]}],"canonical_facts":{"dc:contributor.advisor":["Howard, M.E."],"dc:creator":["Walsh, John Richard"],"dc:date.accessioned":["2018-01-23T19:16:54Z"],"dc:date.available":["2018-01-23T19:16:54Z"],"dc:date.issued":["1951"],"dc:description.abstract":["Systemic lupus erythematosus is a rare disease. And like other rare diseases it becomes scarcer through lack of consideration. Therefore a high index of suspicion is necessary if the diagnosis is to be made more frequently. Before the discovery of a new diagnostic test, acute disseminated lupus erythematosus was a medical curiosity. A few years ago the diagnosis was made with certainty only when the classical picture was encountered. A few astute physicians made the diagnosis in obscure cases but always with some hesitancy. A typical cell was discovered which is diagnostic of the disease and an entity once obscure assumed prominence in medical literature. The profession became more conscious of the disease because with a laboratory procedure there was more confidence in the diagnosis. The realization that the diagnosis has frequently been missed is becoming apparent with the utilization of diagnostic laboratory procedures. | In January 1948, Hargraves, Richmond and Morton announced the discovery of a new cell in bone marrow preparations of patients with acute disseminated lupus erythematosus. Hargraves gave the name L.E. cell to this new entity. A chain of investigations has evolved a new diagnostic procedure for this disease. Lupus erythematosus is now prominent in medical literature and is the subject of a great deal of study. Reports concerning the specificity of this cell for systemic lupus erythematosus are appearing in the literature."],"dc:identifier.uri":["http://hdl.handle.net/10504/115914"],"dc:language.iso":["en_US"],"dc:publisher":["Creighton University"],"dc:rights":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"dc:title":["L.E. Factor Test in Acute Disseminated Lupus Erythematosus"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T01:52:03Z"}