{"id":{"repo_id":"creighton","oai_identifier":"oai:cdr.creighton.edu:10504/110062"},"canonical_url":"https://search.dev.ndltd.org/etd/creighton/oai:cdr.creighton.edu:10504/110062","repository":{"repo_id":"creighton","name":"Creighton University","base_url":"https://cdr.creighton.edu/server/oai/request"},"display":{"title":"Peroxidase Content of Hela Cells During Radiation Injury and Recovery Processes","abstract":"There is no doubt that hydrogen peroxide is the primary molecular product formed by the action of ionizing radiation on oxygenated water. Since living cells always contain and are usually bathed in high concentrations of water and appreciable concentrations of oxygen, the conditions for production of HgOg by radiation are frequently present. A question of interest (Adler, 1963) may be phrased as follows: Does radiation-produced H2O2 have the opportunity to react with critical cell components? The answer to this question depends on (l) knowledge of the concentration and distribution of catalase within and around the cell and (2) understanding of the rate of reaction of hydrogen peroxide with critical cell components as compared to its rate of reaction with catalase.","abstract_html":"There is no doubt that hydrogen peroxide is the primary molecular product formed by the action of ionizing radiation on oxygenated water. Since living cells always contain and are usually bathed in high concentrations of water and appreciable concentrations of oxygen, the conditions for production of HgOg by radiation are frequently present. A question of interest (Adler, 1963) may be phrased as follows: Does radiation-produced H2O2 have the opportunity to react with critical cell components? The answer to this question depends on (l) knowledge of the concentration and distribution of catalase within and around the cell and (2) understanding of the rate of reaction of hydrogen peroxide with critical cell components as compared to its rate of reaction with catalase.","abstract_has_math":false,"creators":["Martinez, Nick Jr."],"institution":"Creighton University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Andrews, Richard V."],"committee_chairs":[],"committee_members":[],"year":1966,"date_issued":"1966","date_published":"1966","updated_at":"2026-07-24T01:50:35Z","subjects":[],"languages":["en_US"],"rights":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10504/110062","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Andrews, Richard V."]},{"key":"dc:creator","label":"Author","values":["Martinez, Nick Jr."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2017-03-21T21:09:46Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2017-03-21T21:09:46Z"]},{"key":"dc:date.issued","label":"Date","values":["1966"]},{"key":"dc:publisher","label":"Institution","values":["Creighton University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_US"]},{"key":"dc:rights","label":"Dc Rights","values":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10504/110062"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["There is no doubt that hydrogen peroxide is the primary molecular product formed by the action of ionizing radiation on oxygenated water. Since living cells always contain and are usually bathed in high concentrations of water and appreciable concentrations of oxygen, the conditions for production of HgOg by radiation are frequently present. A question of interest (Adler, 1963) may be phrased as follows: Does radiation-produced H2O2 have the opportunity to react with critical cell components? The answer to this question depends on (l) knowledge of the concentration and distribution of catalase within and around the cell and (2) understanding of the rate of reaction of hydrogen peroxide with critical cell components as compared to its rate of reaction with catalase."]},{"key":"dc:title","label":"Title","values":["Peroxidase Content of Hela Cells During Radiation Injury and Recovery Processes"]}]}],"canonical_facts":{"dc:contributor.advisor":["Andrews, Richard V."],"dc:creator":["Martinez, Nick Jr."],"dc:date.accessioned":["2017-03-21T21:09:46Z"],"dc:date.available":["2017-03-21T21:09:46Z"],"dc:date.issued":["1966"],"dc:description.abstract":["There is no doubt that hydrogen peroxide is the primary molecular product formed by the action of ionizing radiation on oxygenated water. Since living cells always contain and are usually bathed in high concentrations of water and appreciable concentrations of oxygen, the conditions for production of HgOg by radiation are frequently present. A question of interest (Adler, 1963) may be phrased as follows: Does radiation-produced H2O2 have the opportunity to react with critical cell components? The answer to this question depends on (l) knowledge of the concentration and distribution of catalase within and around the cell and (2) understanding of the rate of reaction of hydrogen peroxide with critical cell components as compared to its rate of reaction with catalase."],"dc:identifier.uri":["http://hdl.handle.net/10504/110062"],"dc:language.iso":["en_US"],"dc:publisher":["Creighton University"],"dc:rights":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"dc:title":["Peroxidase Content of Hela Cells During Radiation Injury and Recovery Processes"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T01:50:35Z"}