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Creighton University

The Preparation of 5-(2',3',4'-Trimethoxyphenyl) -4,6,-Dicarbeth-Oxycyclohexanedione-1,3 and Derivatives

Abstract

dc:description.abstract

One thing that all research projects have in common is a beginning. For the beginning of this project, we must regress over a decade. In 1945 Papadakis synthesized for the first time 5-(p-hydroxyphenyl)-4,6-dicarbethoxycyclohexanadione-1,3, which is the parent substance of several compounds which have been prepared since then. |The original work done by Papadakis was a result of a great interest in substances resembling cardiac glycosides found in the digitalis plant. Fieser and Strain had accumulated all the work done up to that time on the structures, purification, extraction and essential functional groups of these substances. |As one would expect, the next step was to synthesize simpler compounds with the essential functional groups of the natural glycosides.

Degree

thesis:*
Grantor dc:publisher
Creighton University
Year dc:date.issued
1960

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Boand, Wayne M.
Advisor dc:contributor.advisor
  • Papadakis, Phillippos E.

Rights

dc:rights
Statement dc:rights
  • A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above.
Language dc:language.iso
en_US

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/10504/108165
OAI identifier oai:identifier
oai:cdr.creighton.edu:10504/108165

Chain of custody

source
Harvested from
Creighton University
Base URL
cdr.creighton.edu/server/oai/request
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
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citation

Boand, Wayne M.. The Preparation of 5-(2',3',4'-Trimethoxyphenyl) -4,6,-Dicarbeth-Oxycyclohexanedione-1,3 and Derivatives. Creighton University, 1960. http://hdl.handle.net/10504/108165