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Cornell University

EFFECTS OF FEEDING A COMBINATION OF SYNTHETIC ZEOLITE A AND 25 HYDROXYVITAMIN D3 DURING THE PREPARTUM PERIOD ON MINERAL METABOLISM AND LACTATION PERFORMANCE OF HOLSTEIN DAIRY COWS

Abstract

dc:description.abstract

Hypocalcemia during the transition period in dairy cows significantly affects health, reproduction, and milking performance. Although several effective strategies exist to regulate Ca metabolism, the interactions between Ca dynamics, inflammation, and dry matter intake remain poorly understood. This thesis investigates a combination of two commercially validated products; zeolite, a dietary P binding aluminosilicate, and calcidiol, an intermediate vitamin D metabolite. The objectives of our study were to evaluate the effects of the combination of zeolite and calcidiol on mineral metabolism and lactation performance and determine whether this combination is more effective compared to other strategies widely used in dairy farming. In a 2 × 2 factorial experimental design, we investigated the effects of feeding 92 parous close-up dry cows either a negative dietary cation-anion difference diet or a diet with zeolite, with or without calcidiol on milk production and mineral metabolism. Blood samples were collected at select timepoints during the periparturient period. Additionally, daily dry matter intake, milk yield, and rumination, as well as weekly milk composition, body condition scores, and body weights were measured. Data were analyzed using mixed effects models with repeated measures, if applicable, using SAS software. The results indicate that while the combination of zeolite and calcidiol did not improve milk yield in early lactation, zeolite alone significantly increased blood Ca concentrations postpartum.

Degree

thesis:*
Name thesis:degree_name
M.S., Animal Science
Level thesis:degree_level
Master of Science
Discipline thesis:degree_discipline
Animal Science
Grantor
Cornell University
Year dc:date.issued
2025

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Somare, Francisco
Committee members dc:contributor.committeemember
  • Nydam, Daryl
  • Van Amburgh, Michael

Subjects

dc:subject × 4

Rights

Language dc:language.iso
en

Identifiers

dc:identifier.*
Dc Identifier Other
ProQuest Submission ID: 12604
ProQuest Publication ID: 32245676
OAI identifier oai:identifier
oai:ecommons.cornell.edu:1813/120978

Chain of custody

source
Harvested from
Cornell University
Base URL
ecommons.cornell.edu/server/oai/request
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Somare, Francisco. EFFECTS OF FEEDING A COMBINATION OF SYNTHETIC ZEOLITE A AND 25 HYDROXYVITAMIN D3 DURING THE PREPARTUM PERIOD ON MINERAL METABOLISM AND LACTATION PERFORMANCE OF HOLSTEIN DAIRY COWS. Master of Science thesis, Cornell University, 2025. https://hdl.handle.net/1813/120978