Novel insights into the post-translational regulation of an ER localised ubiquitin conjugating enzyme
type: CreativeWork
description: Ube2J1 is an enzyme that helps cells degrade misfolded proteins at the endoplasmic reticulum. This study shows it is controlled by several signalling pathways, and regulated by previously unidentified mechanisms. Ube2J1 also boosts replication of Vesicular Stomatitis Virus when active. These findings reveal wider roles in stress responses, immunity, and disease.
abstract: Ube2J1 is an enzyme that helps cells degrade misfolded proteins at the endoplasmic reticulum. This study shows it is controlled by several signalling pathways, and regulated by previously unidentified mechanisms. Ube2J1 also boosts replication of Vesicular Stomatitis Virus when active. These findings reveal wider roles in stress responses, immunity, and disease.
author: Algoufi, Noor Daifallah
language: en
keywords: ER stress
date published: 2025
date modified: 2026-07-24T01:47:43Z
provider: University College Cork
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University College Cork

PropertyValue
property ID: Handle
value: https://hdl.handle.net/10468/18018