Studies towards the synthesis of trehalamine and the effect of adjacent chiral tertiary and quaternary centers on the metal-catalyzed allylic substitution reaction

Studies were conducted towards advancing a trans-epoxy alcohol, derived from an amino-substituted cyclobutanone, to trehalamine. Efforts to manipulate the epoxy alcohol under standard conditions were hindered by the extraordinary propensity of the system to undergo the Payne rearrangement and the steric environment shielding both the hydroxyl group and the epoxide.

Name thesis:degree_name

Doctor of Philosophy (Ph.D.)

Level thesis:degree_level

Doctoral

Discipline thesis:degree_discipline

Chemistry

Grantor dc:publisher

Colorado State University. Libraries

Year dc:date.issued

2002

Authors dc:creator

• Sebahar, Holly Lynn, author
• Hegedus, Louis, advisor

• organic chemistry

Statement dc:rights

• Copyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.

Language dc:language.iso

eng, English

Identifier URI

https://doi.org/10.25675/3.025746

OAI identifier oai:identifier

oai:mountainscholar.org:10217/242889