Integrating AI and GIS for Climate-Driven Malaria Monitoring and Demand-Based Resource Distribution and Supply Optimization in Low Developing Countries

<p>Malaria remains a critical public health challenge in Uganda—responsible for an estimated 13.2 million cases annually yet control efforts are continually undermined by climate variability and systemic supply chain failures. This study investigated the relationship between climatic variables (rainfall, temperature, humidity) and malaria incidence, evaluated the efficacy of the current supply management system, and assessed how AI-predictive models and GIS tools can optimize resource distribution. Employing a multi-scalar mixed-methods approach, the research utilized Spatial Autoregressive Models (SAR), Geographically Weighted Regression (GWR), and Random Forest machine learning (R2 = .86) to analyze transmission dynamics. Key findings reveal that minimum temperature is the strongest predictor of transmission (p < .001), while rainfall acts as a reliable 30-day (Lag-1) lead indicator. Emerging Hot Spot Analysis (EHSA) isolated 11 "Intensifying" districts requiring immediate saturation and 32 "Sporadic" zones driven by seasonal volatility. Furthermore, the evaluation of the current supply system exposed a "phantom mortality reduction," where rising stockouts (averaging 53 consecutive days in the Central Region) artificially lowered reported deaths. Significantly, a spatial spillover effect (rho = 0.27) confirmed that uncoordinated interventions fail as high-burden districts export risk to neighboring areas. This research provides three major advancements: methodologically, it combines spatial econometrics with machine learning for high-precision risk forecasting; practically, it introduces an AI-GIS dashboard and Early Warning System to enable a "Self-Healing Supply Chain" and theoretically, the research extends the Health System Resilience Theory established by Kruk et al. (2015) and Blanchet et al. (2017) by introducing the Adaptive Digital Resilience Model (ADRM). Despite these technical gains, the study notes that successful "last mile" delivery depends on closing the digital divide among Village Health Teams (VHTs) to protect the most vulnerable populations.</p>

Name thesis:degree_name

Information Systems and Technology, PhD

Level thesis:degree_level

Open Access Dissertation

Discipline thesis:degree_discipline

Center for Information Systems and Technology

Year dc:date.available

2026

Author dc:creator

• Komugabe, Maria Assumpta

Contributors dc:contributor

• Warren Roberts
• Zachary Dodds
• Julie Medero & Conrad Shayo

• Geographically Weighted Regression
• GIS
• Machine learning/GEOAI
• Malaria Monitoring
• Random Forest machine learning
• Spatial Autoregressive Models
• Geographic Information Sciences
• Public Health

Repository record dc:identifier

https://scholarship.claremont.edu/cgu_etd/1110

OAI identifier oai:identifier

oai:scholarship.claremont.edu:cgu_etd-2132