Increased Utility of pH Sensitive Indicators as High Concentration CO2 Detectors Through the Use of Polyelectrolyte Complexes as Stabilizing Media

Development of plastic materials which produce visible color change when exposed to different environments has recently attracted attention for many biomedical applications.^1,2Many biomedical devices are packaged under high concentrations of carbon dioxide (CO₂) which can lower the pH of the packaging environment. This is similar to the CO₂ chemistry responsible for ocean acidification.³ Dye molecules that are sensitive to environmental changes in pH (known as pH indicators) can be encapsulated in plastics and produce a visible color change when a medical device is removed from the sterile CO₂ environment. Plastics made from large molecules known as polyelectrolytes can form complexes which may serve as inexpensive and multipurpose mediums for encapsulation of pH sensitive indicators. This research aims to combine the properties of both pH indicators and polyelectrolyte complexes (PECs) to form a stable plastic which will contain indicators sensitive to CO₂ environments and slowly change color over extended periods of time, increasing the durability and usefulness in many such biomedical applications. Characterization of the physical properties of indicator containing polyelectrolyte complexes (ICPECs) was performed via scanning electron microscopy (SEM) in order to determine properties such as pore size. Compositional analysis of the ICPEC was performed via attenuated total reflection infrared spectroscopy (ATR-FTIR) and simultaneous thermal analysis (STA). It was shown that ICPECs are very dependent on both internal ionic concentration and moisture content and that these factors can significantly influence the rate at which ICPECs respond to introduction to high concentration CO₂ environments such as are found in many biomedical applications.

Name thesis:degree_name

Master of Science (MS)

Discipline thesis:degree_discipline

Chemistry

Year dc:date.available

2019

Author dc:creator

• Johnson, Camden James

Contributors dc:contributor

• Dion Rivera
• JoAnn Peters
• Yingbin Ge

• polyelectrolyte complex
• polymer
• carbon dioxide
• detection
• Analytical Chemistry
• Inorganic Chemistry
• Materials Chemistry
• Polymer Chemistry

Language dc:language

English

Repository record dc:identifier

https://digitalcommons.cwu.edu/etd/1195

OAI identifier oai:identifier

oai:digitalcommons.cwu.edu:etd-2216