{"id":{"repo_id":"cau-kiel","oai_identifier":"oai:macau.uni-kiel.de:macau_mods_00008388"},"canonical_url":"https://search.dev.ndltd.org/etd/cau-kiel/oai:macau.uni-kiel.de:macau_mods_00008388","repository":{"repo_id":"cau-kiel","name":"Christian-Albrechts Universität Kiel","base_url":"https://macau.uni-kiel.de/servlets/OAIDataProvider"},"display":{"title":"Signatures of gut microbes in human diseases","abstract":"The human body constitutes a complex ecosystem inhabited by a vast and diverse community of microorganisms. Through evolution, host-microbe interactions have been shaped toward mutually beneficial relationships that support host health. Consequently, perturbations of the microbial compartment are increasingly recognized as contributing factors in a wide range of human diseases. This work investigates how bacteria residing in the human large intestine – home to the densest microbial community in the body – contribute to the pathogenesis of three distinct conditions: Parkinson’s disease (PD), inflammatory bowel diseases (IBD), and colorectal cancer (CRC).","abstract_html":"The human body constitutes a complex ecosystem inhabited by a vast and diverse community of microorganisms. Through evolution, host-microbe interactions have been shaped toward mutually beneficial relationships that support host health. Consequently, perturbations of the microbial compartment are increasingly recognized as contributing factors in a wide range of human diseases. This work investigates how bacteria residing in the human large intestine – home to the densest microbial community in the body – contribute to the pathogenesis of three distinct conditions: Parkinson’s disease (PD), inflammatory bowel diseases (IBD), and colorectal cancer (CRC).","abstract_has_math":false,"creators":["Quevedo Olmos, Alvaro"],"institution":"Christian-Albrechts-Universität zu Kiel","degree_name":null,"degree_level":"thesis.doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":["Meyer, Thomas F.","Schulenburg, Hinrich","Dagan, Tal"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2026,"date_issued":"2026-05-12","date_published":"2026-05-12","updated_at":"2026-07-24T01:35:26Z","subjects":["Metagenome","Parkinson's Disease","IBD"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://macau.uni-kiel.de/receive/macau_mods_00008388","outbound_label":"Repository record","outbound_source":"source_url"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Meyer, Thomas F.","Schulenburg, Hinrich","Dagan, Tal"]},{"key":"dc:creator","label":"Author","values":["Quevedo Olmos, Alvaro"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:publisher","label":"Institution","values":["Universitätsbibliothek Kiel"]},{"key":"dc:type","label":"Dc Type","values":["PhDThesis"]},{"key":"thesis:degree_level","label":"Degree Level","values":["thesis.doctoral"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Christian-Albrechts-Universität zu Kiel"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Metagenome","Parkinson's Disease","IBD"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The human body constitutes a complex ecosystem inhabited by a vast and diverse community of microorganisms. Through evolution, host-microbe interactions have been shaped toward mutually beneficial relationships that support host health. Consequently, perturbations of the microbial compartment are increasingly recognized as contributing factors in a wide range of human diseases. This work investigates how bacteria residing in the human large intestine – home to the densest microbial community in the body – contribute to the pathogenesis of three distinct conditions: Parkinson’s disease (PD), inflammatory bowel diseases (IBD), and colorectal cancer (CRC)."]},{"key":"dc:format.medium","label":"Dc Format Medium","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Signatures of gut microbes in human diseases"]}]}],"canonical_facts":{"dc:contributor":["Meyer, Thomas F.","Schulenburg, Hinrich","Dagan, Tal"],"dc:creator":["Quevedo Olmos, Alvaro"],"dc:description.abstract":["The human body constitutes a complex ecosystem inhabited by a vast and diverse community of microorganisms. Through evolution, host-microbe interactions have been shaped toward mutually beneficial relationships that support host health. Consequently, perturbations of the microbial compartment are increasingly recognized as contributing factors in a wide range of human diseases. This work investigates how bacteria residing in the human large intestine – home to the densest microbial community in the body – contribute to the pathogenesis of three distinct conditions: Parkinson’s disease (PD), inflammatory bowel diseases (IBD), and colorectal cancer (CRC)."],"dc:format.medium":["application/pdf"],"dc:publisher":["Universitätsbibliothek Kiel"],"dc:subject":["Metagenome","Parkinson's Disease","IBD"],"dc:title":["Signatures of gut microbes in human diseases"],"dc:type":["PhDThesis"],"thesis:degree_level":["thesis.doctoral"],"thesis:institution_name":["Christian-Albrechts-Universität zu Kiel"]},"updated_at":"2026-07-24T01:35:26Z"}