Carleton University
4D Monte Carlo Based Patient Dose Reconstruction Incorporating Surface Motion Measurements
Abstract
dc:description.abstractA framework was developed to assess the impact of respiratory motion on the dose delivered during radiotherapy using a previously validated 4D Monte Carlo-based dose reconstruction tool, 4Ddefdosxyznrc. As a surrogate for tumour motion, abdominal surface motion measurements were recorded during patient treatments using the RADPOS system. Motion traces, treatment log files and deformation vectors representing each patient's respiratory motion were used as inputs to the 4D dose reconstructions. Motion measurements were performed for 3 patients undergoing radiation therapy for non-small cell lung cancer, totalling 12 fractions. No statistically significant inter-fractional differences in 4D reconstructed dose metrics were found. A maximum difference of 2.0% in the GTV D98% was found between 4D calculations and the treatment planning system. This result is consistent with small abdominal displacements of 5.5 ± 1.4 mm, 5.4 ± 0.4 mm, and 0.40 ± 0.03 mm, respectively, observed for these 3 patients during treatments.
Degree
thesis:*- Name thesis:degree_name
- Master of Science (M.Sc.)
- Level thesis:degree_level
- Master's
- Discipline thesis:degree_discipline
- Physics
- Grantor dc:publisher
- Carleton University
- Year dc:date.issued
- 2022
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Shiha, Meaghen
Rights
dc:rights- Statement dc:rights
-
- Copyright © 2022 the author(s). Theses may be used for non-commercial research, educational, or related academic purposes only. Such uses include personal study, research, scholarship, and teaching. Theses may only be shared by linking to Carleton University Institutional Repository and no part may be used without proper attribution to the author. No part may be used for commercial purposes directly or indirectly via a for-profit platform; no adaptation or derivative works are permitted without consent from the copyright owner.
- Language dc:language.iso
- en
Identifiers
dc:identifier.*- OAI identifier oai:identifier
- oai:carleton.scholaris.ca:20.500.14718/42294