Associations of severe hyperlactataemia and lactic acidosis in HIV-infected patients receiving antiretroviral theraphy

Severe symptomatic hyperlactataemia and lactic acidosis (SHLA) are life-threatening events that are occurring at increasing incidence levels in South Africa. Globally, the rise in SHLA cases is closely correlated to the increased accessibility of anti retroviral (ARV) medication for human immunodeficiency virus (HIV). Although hyperlactataemia and lactic acidosis were once thought of as rare conditions, they are now being recognized as important concerns when administering antiretroviral therapy. A better understanding of the risk factors for SHLA is important in combating the morbidity and mortality associated with such an adverse event.

Grantor dc:publisher.institution

Department of Public Health and Family Medicine

Year dc:date.issued

2007

Author dc:creator

• Osler, Meg

Advisor dc:contributor.advisor

• Boulle, Andrew

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/7438

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/7438