An investigation into the development of plant-derived vaccines against human papillomavirus type 11 and Cottontail rabbit papillomavirus
The principal object of this thesis was to investigate the feasibility of developing a novel plant-derived vaccine against Human papillomavirus type 11 (HPV -11), the causal agent of genital warts and laryngeal condylomas. A secondary objective was a proof-of-concept study using Cottontail rabbit papillomavirus (CRPV), as this is a viable animal model for human papillomavirus vaccines. Accordingly, I investigated and compared the potential of two different plant expression systems.
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Department of Molecular and Cell Biology