{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/7433"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/7433","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"An investigation into the development of plant-derived vaccines against human papillomavirus type 11 and Cottontail rabbit papillomavirus","abstract":"The principal object of this thesis was to investigate the feasibility of developing a novel plant-derived vaccine against Human papillomavirus type 11 (HPV -11), the causal agent of genital warts and laryngeal condylomas. A secondary objective was a proof-of-concept study using Cottontail rabbit papillomavirus (CRPV), as this is a viable animal model for human papillomavirus vaccines. 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A secondary objective was a proof-of-concept study using Cottontail rabbit papillomavirus (CRPV), as this is a viable animal model for human papillomavirus vaccines. Accordingly, I investigated and compared the potential of two different plant expression systems."]},{"key":"dc:title","label":"Title","values":["An investigation into the development of plant-derived vaccines against human papillomavirus type 11 and Cottontail rabbit papillomavirus"]}]}],"canonical_facts":{"dc:contributor.advisor":["Rybicki, Ed","Becker-Hitzeroth, Inga I"],"dc:creator":["Kohl, Thomas Oliver"],"dc:date.accessioned":["2014-09-12T07:03:17Z"],"dc:date.available":["2014-09-12T07:03:17Z"],"dc:date.issued":["2004"],"dc:description":["Includes bibliographical references (leaves 207-241)."],"dc:description.abstract":["The principal object of this thesis was to investigate the feasibility of developing a novel plant-derived vaccine against Human papillomavirus type 11 (HPV -11), the causal agent of genital warts and laryngeal condylomas. 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