Small molecule inhibitors of parasitic enzymes

The work presented in this thesis is threefold:-(i) development of potential novel inhibitors of cysteine proteases from the causative agents of Malaria, African sleeping sickness and Chagas disease, (ii) development of potential new and novel anti-trypanosomal inhibitors of trypanosome alternative oxidase, and (ii) synthetic and methodological studies.

Grantor dc:publisher.institution

Department of Chemistry

Year dc:date.issued

2005

Author dc:creator

• Chipeleme, Alex

Advisor dc:contributor.advisor

• Chibale, Kelly

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/6298

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/6298