Synthesis, characterization, biological and catalytic studies of tridentate monothiosemicarbazone palladium (II) complexes

Nine monothiosemicarbazone ligands were prepared by Schiff-base condensation reactions of thiosemicarbazide and the appropriate aryl aldehyde or ketone. These compounds were isolated as air- and moisture- stable solids and were characterized using NMR and IR spectroscopies, as well as mass spectrometry and elemental analysis in the case of ligand 3-terl.-butyl-2-hydroxy-benzaldehyde thiosemicarbazone, which is a new compound. Four of these ligands were reacted with precursors of type Pd(L)2CI2 yielding eight tridentate thiosemicarbazone Pd(II) complexes with general formula [Pd( 3-0,N,Sthiosemicarbazone)(L)] (L = PPh3 or 4-picoline). Six of these complexes are new compounds and were fully characterized using NMR and IR spectroscopies, mass spectrometry and elemental analysis. In addition, the solid state structures of three complexes were elucidated using single crystal X-ray diffraction methods.

Grantor dc:publisher.institution

Department of Chemistry

Year dc:date.issued

2009

Author dc:creator

• Chellan, Prinessa

Advisors dc:contributor.advisor

• Smith, Gregory S
• Chibale, Kelly

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/6297

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/6297