{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/5967"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/5967","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Characterisation of the role of brain factor 1 in the olfactory neuroepithelium during neuronal development","abstract":"Brain Factor 1 (BF-1), a winged helix transcription factor, displays a restricted pattern of expression within the developing forebrain, playing a critical function in the regulation of neuronal progenitor cell proliferation and differentiation within the developing forebrain. The molecular mechanisms by which BF-1 carries out its function remain to be elucidated. Hence, this study aimed to investigate and characterise the molecular mechanisms by which BF-1 function is regulated during neuronal development.","abstract_html":"Brain Factor 1 (BF-1), a winged helix transcription factor, displays a restricted pattern of expression within the developing forebrain, playing a critical function in the regulation of neuronal progenitor cell proliferation and differentiation within the developing forebrain. The molecular mechanisms by which BF-1 carries out its function remain to be elucidated. Hence, this study aimed to investigate and characterise the molecular mechanisms by which BF-1 function is regulated during neuronal development.","abstract_has_math":false,"creators":["Linda, Pride"],"institution":"Department of Molecular and Cell Biology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Illing, Nicola","Patterton, Hugh"],"committee_chairs":[],"committee_members":[],"year":2003,"date_issued":"2003","date_published":"2003","updated_at":"2026-07-22T22:22:44Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/5967","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Illing, Nicola","Patterton, Hugh"]},{"key":"dc:creator","label":"Author","values":["Linda, Pride"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-08-02T14:56:35Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-08-02T14:56:35Z"]},{"key":"dc:date.issued","label":"Date","values":["2003"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Molecular and Cell Biology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MSc"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/5967"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Bibliography: leaves 147-152."]},{"key":"dc:description.abstract","label":"Abstract","values":["Brain Factor 1 (BF-1), a winged helix transcription factor, displays a restricted pattern of expression within the developing forebrain, playing a critical function in the regulation of neuronal progenitor cell proliferation and differentiation within the developing forebrain. The molecular mechanisms by which BF-1 carries out its function remain to be elucidated. Hence, this study aimed to investigate and characterise the molecular mechanisms by which BF-1 function is regulated during neuronal development."]},{"key":"dc:title","label":"Title","values":["Characterisation of the role of brain factor 1 in the olfactory neuroepithelium during neuronal development"]}]}],"canonical_facts":{"dc:contributor.advisor":["Illing, Nicola","Patterton, Hugh"],"dc:creator":["Linda, Pride"],"dc:date.accessioned":["2014-08-02T14:56:35Z"],"dc:date.available":["2014-08-02T14:56:35Z"],"dc:date.issued":["2003"],"dc:description":["Bibliography: leaves 147-152."],"dc:description.abstract":["Brain Factor 1 (BF-1), a winged helix transcription factor, displays a restricted pattern of expression within the developing forebrain, playing a critical function in the regulation of neuronal progenitor cell proliferation and differentiation within the developing forebrain. The molecular mechanisms by which BF-1 carries out its function remain to be elucidated. Hence, this study aimed to investigate and characterise the molecular mechanisms by which BF-1 function is regulated during neuronal development."],"dc:identifier.uri":["http://hdl.handle.net/11427/5967"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Molecular and Cell Biology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["Characterisation of the role of brain factor 1 in the olfactory neuroepithelium during neuronal development"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MSc"]},"updated_at":"2026-07-22T22:22:44Z"}