Peripheral blood mononuclear cells as non-invasive diagnostic indicators of stress-associated neural states

Researchers have demonstrated the ability to predict psychopathological states from human peripheral immune tissure transcriptional profiles, using microarrays. Although evidence in support of such an approach as a viable diagnostic avenue within psychiatric settings is accumulating, it remains to be demonstrated, in an animal model, that transcriptional changes in peripheral tissue targets are paralleled by specific gene expression changes in neural tissues.

Grantor dc:publisher.institution

Department of Molecular and Cell Biology

Year dc:date.issued

2008

Author dc:creator

• Van Heerden, Johannes Hendrik

Advisors dc:contributor.advisor

• Illing, Nicola
• Stein, Dan

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/4347

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/4347