{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/42299"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/42299","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country","abstract":"Background: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, South Africa. Methods: We conducted a retrospective observational study of patients admitted with ACS to the Department of Medicine at Victoria Hospital, Cape Town, from the 1 st September 2020 to 30 November 2020. Results: Eighty eight patients with a diagnosis of ACS was admitted, of who 52 had NSTEMI/UAP and 36 patients had STEMI. The median age was 60 years, with a male predominance of 61.36%. The major risk factors for CAD were hypertension and smoking. The overall 1-month, 6-month, and 12-month mortality rates for our cohort were 4%, 17%, and 19%, respectively. Patients that received coronary intervention (thrombolytics/PCI/CABG) had better outcomes than in those who were managed conservatively. Conclusion: This study describes the experience of ACS management in a resource-limited public hospital in Cape Town, South Africa. Our patients had multiple cardiovascular risk factors with a higher mortality than published data. The lack of receiving coronary intervention was associated with worse outcomes.","abstract_html":"Background: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, South Africa. Methods: We conducted a retrospective observational study of patients admitted with ACS to the Department of Medicine at Victoria Hospital, Cape Town, from the 1 st September 2020 to 30 November 2020. Results: Eighty eight patients with a diagnosis of ACS was admitted, of who 52 had NSTEMI/UAP and 36 patients had STEMI. The median age was 60 years, with a male predominance of 61.36%. The major risk factors for CAD were hypertension and smoking. The overall 1-month, 6-month, and 12-month mortality rates for our cohort were 4%, 17%, and 19%, respectively. Patients that received coronary intervention (thrombolytics/PCI/CABG) had better outcomes than in those who were managed conservatively. Conclusion: This study describes the experience of ACS management in a resource-limited public hospital in Cape Town, South Africa. Our patients had multiple cardiovascular risk factors with a higher mortality than published data. The lack of receiving coronary intervention was associated with worse outcomes.","abstract_has_math":false,"creators":["Govender, Kamini"],"institution":"Department of Medicine","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Van Der Schyff, Nasief","Engel, Mark"],"committee_chairs":[],"committee_members":[],"year":2025,"date_issued":"2025","date_published":"2025","updated_at":"2026-07-22T22:23:02Z","subjects":["acute coronary syndrome","outcomes","ischemic heart disease","mortality","MACE"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/42299","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Van Der Schyff, Nasief","Engel, Mark"]},{"key":"dc:creator","label":"Author","values":["Govender, Kamini"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2025-11-21T13:03:48Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2025-11-21T13:03:48Z"]},{"key":"dc:date.issued","label":"Date","values":["2025"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Medicine"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Thesis / Dissertation"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters","MMed"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["acute coronary syndrome","outcomes","ischemic heart disease","mortality","MACE"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/42299"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Background: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, South Africa. Methods: We conducted a retrospective observational study of patients admitted with ACS to the Department of Medicine at Victoria Hospital, Cape Town, from the 1 st September 2020 to 30 November 2020. Results: Eighty eight patients with a diagnosis of ACS was admitted, of who 52 had NSTEMI/UAP and 36 patients had STEMI. The median age was 60 years, with a male predominance of 61.36%. The major risk factors for CAD were hypertension and smoking. The overall 1-month, 6-month, and 12-month mortality rates for our cohort were 4%, 17%, and 19%, respectively. Patients that received coronary intervention (thrombolytics/PCI/CABG) had better outcomes than in those who were managed conservatively. Conclusion: This study describes the experience of ACS management in a resource-limited public hospital in Cape Town, South Africa. Our patients had multiple cardiovascular risk factors with a higher mortality than published data. The lack of receiving coronary intervention was associated with worse outcomes."]},{"key":"dc:title","label":"Title","values":["Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country"]}]}],"canonical_facts":{"dc:contributor.advisor":["Van Der Schyff, Nasief","Engel, Mark"],"dc:creator":["Govender, Kamini"],"dc:date.accessioned":["2025-11-21T13:03:48Z"],"dc:date.available":["2025-11-21T13:03:48Z"],"dc:date.issued":["2025"],"dc:description.abstract":["Background: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, South Africa. Methods: We conducted a retrospective observational study of patients admitted with ACS to the Department of Medicine at Victoria Hospital, Cape Town, from the 1 st September 2020 to 30 November 2020. Results: Eighty eight patients with a diagnosis of ACS was admitted, of who 52 had NSTEMI/UAP and 36 patients had STEMI. The median age was 60 years, with a male predominance of 61.36%. The major risk factors for CAD were hypertension and smoking. The overall 1-month, 6-month, and 12-month mortality rates for our cohort were 4%, 17%, and 19%, respectively. Patients that received coronary intervention (thrombolytics/PCI/CABG) had better outcomes than in those who were managed conservatively. Conclusion: This study describes the experience of ACS management in a resource-limited public hospital in Cape Town, South Africa. Our patients had multiple cardiovascular risk factors with a higher mortality than published data. The lack of receiving coronary intervention was associated with worse outcomes."],"dc:identifier.uri":["http://hdl.handle.net/11427/42299"],"dc:language.iso":["en"],"dc:publisher.department":["Department of Medicine"],"dc:publisher.institution":["University of Cape Town"],"dc:subject":["acute coronary syndrome","outcomes","ischemic heart disease","mortality","MACE"],"dc:title":["Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country"],"dc:type":["Thesis / Dissertation"],"dc:type.qualificationlevel":["Masters","MMed"]},"updated_at":"2026-07-22T22:23:02Z"}