Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country

Objective: To evaluate the impact of small for gestational age on outcomes of very low birth weight infants at Groote Schuur Hospital, Cape Town, South Africa. Study design: Data was obtained from Vermont Oxford Network Groote Schuur Hospital database from 2012 to 2018. Fenton growth charts were used to define small for gestational age as birth weight < 10th centile for gestational age. Results: Mortality (28.9% vs 18.5%, adjusted risk ratio (aRR) 2.1, 95% confidence interval (CI) 1.6-2.7), bronchopulmonary dysplasia (14% vs 4.5%, aRR 3.7, 95% CI 2.3-6.1) and late onset sepsis (16.7% vs 9.6%, aRR 2.3, 95% CI 1.6-3.3) were higher in the small for gestational age than in the non-small for gestational age group. Conclusion: Small for gestational age infants have a higher risk of mortality and morbidity among very low birth weight infants at Groote Schuur Hospital. This may be useful for counseling and perinatal management.

Grantor

Department of Paediatrics and Child Health

Year dc:date.issued

2021

Author dc:creator

• Mangiza, Marcia

Advisors dc:contributor.advisor

• Tooke, Lloyd
• Rhoda, Natasha Raygaan

• Neonatology

Handle dc:identifier.uri

http://hdl.handle.net/11427/35939

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/35939