{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/3431"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/3431","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"A study of defibrillator waveforms, vectors, and therapies Kevin Anthony Michael.","abstract":"The defibrillation studies were performed in a porcine model given its resemblance to the human heart and its resilience to repeated ventricular fibrillation inductions (VF) and defibrillations. A novel sequential preshock waveform was assessed in a prototype serial capacitance device. Single and multi-electrode defibrillation vectors were evaluated in intra-cardiac, subcutaneous (SQ), and intra-pericardial configurations. The burden of ITS and the factors improving detection were assessed. Anti-tachycardia pacing was used to evaluate therapies in this patient cohort. The diagnostic utility of the post pacing interval (PPI) after failed ATP episodes was then investigated to help discriminate between atrial fibrillation/tachycardia (AF/AT) and VT.","abstract_html":"The defibrillation studies were performed in a porcine model given its resemblance to the human heart and its resilience to repeated ventricular fibrillation inductions (VF) and defibrillations. A novel sequential preshock waveform was assessed in a prototype serial capacitance device. Single and multi-electrode defibrillation vectors were evaluated in intra-cardiac, subcutaneous (SQ), and intra-pericardial configurations. The burden of ITS and the factors improving detection were assessed. Anti-tachycardia pacing was used to evaluate therapies in this patient cohort. The diagnostic utility of the post pacing interval (PPI) after failed ATP episodes was then investigated to help discriminate between atrial fibrillation/tachycardia (AF/AT) and VT.","abstract_has_math":false,"creators":["Michael, Kevin Anthony"],"institution":"Department of Medicine","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Morgan, John","Roberts, Paul"],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012","date_published":"2012","updated_at":"2026-07-22T22:23:39Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/3431","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Morgan, John","Roberts, Paul"]},{"key":"dc:creator","label":"Author","values":["Michael, Kevin Anthony"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-07-29T09:07:24Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-07-29T09:07:24Z"]},{"key":"dc:date.issued","label":"Date","values":["2012"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Medicine"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Doctoral Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["DMed"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/3431"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Includes abstract.","Includes bibliographical references."]},{"key":"dc:description.abstract","label":"Abstract","values":["The defibrillation studies were performed in a porcine model given its resemblance to the human heart and its resilience to repeated ventricular fibrillation inductions (VF) and defibrillations. A novel sequential preshock waveform was assessed in a prototype serial capacitance device. Single and multi-electrode defibrillation vectors were evaluated in intra-cardiac, subcutaneous (SQ), and intra-pericardial configurations. The burden of ITS and the factors improving detection were assessed. Anti-tachycardia pacing was used to evaluate therapies in this patient cohort. The diagnostic utility of the post pacing interval (PPI) after failed ATP episodes was then investigated to help discriminate between atrial fibrillation/tachycardia (AF/AT) and VT."]},{"key":"dc:title","label":"Title","values":["A study of defibrillator waveforms, vectors, and therapies Kevin Anthony Michael."]}]}],"canonical_facts":{"dc:contributor.advisor":["Morgan, John","Roberts, Paul"],"dc:creator":["Michael, Kevin Anthony"],"dc:date.accessioned":["2014-07-29T09:07:24Z"],"dc:date.available":["2014-07-29T09:07:24Z"],"dc:date.issued":["2012"],"dc:description":["Includes abstract.","Includes bibliographical references."],"dc:description.abstract":["The defibrillation studies were performed in a porcine model given its resemblance to the human heart and its resilience to repeated ventricular fibrillation inductions (VF) and defibrillations. A novel sequential preshock waveform was assessed in a prototype serial capacitance device. Single and multi-electrode defibrillation vectors were evaluated in intra-cardiac, subcutaneous (SQ), and intra-pericardial configurations. The burden of ITS and the factors improving detection were assessed. Anti-tachycardia pacing was used to evaluate therapies in this patient cohort. The diagnostic utility of the post pacing interval (PPI) after failed ATP episodes was then investigated to help discriminate between atrial fibrillation/tachycardia (AF/AT) and VT."],"dc:identifier.uri":["http://hdl.handle.net/11427/3431"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Medicine"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["A study of defibrillator waveforms, vectors, and therapies Kevin Anthony Michael."],"dc:type":["Doctoral Thesis"],"dc:type.qualificationlevel":["Doctoral"],"dc:type.qualificationname":["DMed"]},"updated_at":"2026-07-22T22:23:39Z"}