Variegate porphyria : molecular aspects of variegate porphyria in South Africa and their biochemical and clinical consequences

Variegate porphyria (VP) is the clinical disorder associated with a deficiency of the haemsynthesising enzyme protoporphyrinogen oxidase (PPO). VP is one of the commonest monogenic inherited disorders in South Africa. The clinical effects include photocutaneous sensitivity and the development of potentially life-threatening acute porphyric crises. Section 1 of this dissertation examines the molecular basis for VP in South Africa.

Grantor dc:publisher.institution

Department of Medicine

Year dc:date.issued

2000

Author dc:creator

• Hift, R J

Advisor dc:contributor.advisor

• Kirsch, Ralph

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/3398

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/3398