{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/31753"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/31753","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Juvenile myoclonic epilepsy : characterisation of the syndrome and examination of linkage to the HLA locus in families from the Western Cape","abstract":"The primary purpose of this study was the identification of patients with JME, in order to identify suitable families for studying the nature of the linkage of the syndrome of JME to the HLA (Human Leukocyte Antigen) locus. This search for suitable candidate families necessitated examination of a large number of individuals with a range of IGE syndromes, and patients were classified into these various syndromes. Patients with JME were thereafter investigated further. The study could thus be broken up into three sections: i) Determination of the various syndromes of IGE. ii) Characterisation of JME. iii) Linkage Studies on JME patients.","abstract_html":"The primary purpose of this study was the identification of patients with JME, in order to identify suitable families for studying the nature of the linkage of the syndrome of JME to the HLA (Human Leukocyte Antigen) locus. This search for suitable candidate families necessitated examination of a large number of individuals with a range of IGE syndromes, and patients were classified into these various syndromes. Patients with JME were thereafter investigated further. The study could thus be broken up into three sections: i) Determination of the various syndromes of IGE. ii) Characterisation of JME. iii) Linkage Studies on JME patients.","abstract_has_math":false,"creators":["Carr, Jonathan Ambrose"],"institution":"Department of Medicine","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Eastman, Roland"],"committee_chairs":[],"committee_members":[],"year":1997,"date_issued":"1997","date_published":"1997","updated_at":"2026-07-22T22:23:13Z","subjects":["Epilepsy"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/11427/31753","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Eastman, Roland"]},{"key":"dc:creator","label":"Author","values":["Carr, Jonathan Ambrose"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2020-05-02T14:45:27Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2020-05-02T14:45:27Z"]},{"key":"dc:date.issued","label":"Date","values":["1997"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Medicine"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Epilepsy"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/11427/31753"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The primary purpose of this study was the identification of patients with JME, in order to identify suitable families for studying the nature of the linkage of the syndrome of JME to the HLA (Human Leukocyte Antigen) locus. This search for suitable candidate families necessitated examination of a large number of individuals with a range of IGE syndromes, and patients were classified into these various syndromes. Patients with JME were thereafter investigated further. The study could thus be broken up into three sections: i) Determination of the various syndromes of IGE. ii) Characterisation of JME. iii) Linkage Studies on JME patients."]},{"key":"dc:title","label":"Title","values":["Juvenile myoclonic epilepsy : characterisation of the syndrome and examination of linkage to the HLA locus in families from the Western Cape"]}]}],"canonical_facts":{"dc:contributor.advisor":["Eastman, Roland"],"dc:creator":["Carr, Jonathan Ambrose"],"dc:date.accessioned":["2020-05-02T14:45:27Z"],"dc:date.available":["2020-05-02T14:45:27Z"],"dc:date.issued":["1997"],"dc:description.abstract":["The primary purpose of this study was the identification of patients with JME, in order to identify suitable families for studying the nature of the linkage of the syndrome of JME to the HLA (Human Leukocyte Antigen) locus. This search for suitable candidate families necessitated examination of a large number of individuals with a range of IGE syndromes, and patients were classified into these various syndromes. Patients with JME were thereafter investigated further. The study could thus be broken up into three sections: i) Determination of the various syndromes of IGE. ii) Characterisation of JME. iii) Linkage Studies on JME patients."],"dc:identifier.uri":["https://hdl.handle.net/11427/31753"],"dc:publisher.department":["Department of Medicine"],"dc:subject":["Epilepsy"],"dc:title":["Juvenile myoclonic epilepsy : characterisation of the syndrome and examination of linkage to the HLA locus in families from the Western Cape"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"]},"updated_at":"2026-07-22T22:23:13Z"}