Altered protein expression patterns in oesophageal cancer

Oesophageal squamous cell carcinoma presents a significant health burden in South Africa. It is one of the most common causes of cancer-related mortality of South African black males, as a result of its asymptomatic progression leading to late diagnosis and poor prognosis. The aim of this study was to identify membrane or membrane-associated proteins that are expressed at different levels in oesophageal tumour tissue when compared to normal tissue. The identification of such proteins would be an important step towards the development of better diagnostic and therapeutic strategies for this disease. Two proteomic approaches, were employed to identify differentially expressed proteins.

Grantor dc:publisher.institution

Division of Medical Biochemistry

Year dc:date.issued

2009

Author dc:creator

• Zemanay, Widaad

Advisor dc:contributor.advisor

• Hendricks, Denver

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/3157

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/3157