{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/3036"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/3036","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"The effect of HIV infection on the incidence and severity of post-partum haemorrhage","abstract":"Postpartum haemorrhage (PPH) accounts for more than 75% of maternal deaths from obstetric haemorrhage. In South Africa, maternal mortality resulting from postpartum haemorrhage has persistently been shown to be higher in HIV positive compared to HIV negative women. It is unknown whether the incidence of PPH is higher in HIV positive women; and/or whether HIV positive women have more severe bleeding and suffer greater morbidity as a result of PPH. The aim of the study was to investigate the effect of HIV infection on the incidence and severity of PPH. All women delivering at Mowbray Maternity and Groote Schuur Hospital in 2009 who had PPH were identified through a manual search of labour ward and operating theatre records. The women were categorized according to their HIV status as HIV positive, negative and untested. Data was also obtained on HIV status of the whole delivery population at these two hospitals. For women with PPH, data regarding background characteristics:- blood loss; cause of PPH and management provided; severity of and morbidity from PPH was analysed by comparing the HIV positive with the HIV negative group. Severity was assessed in terms of blood loss alone. Morbidity on the other hand was a composite assessment of blood loss, need for blood products, interventions required and complications of the PPH. Data was also collected on CD4 counts and treatment provided although the study was not powered to investigate these factors as associations.","abstract_html":"Postpartum haemorrhage (PPH) accounts for more than 75% of maternal deaths from obstetric haemorrhage. In South Africa, maternal mortality resulting from postpartum haemorrhage has persistently been shown to be higher in HIV positive compared to HIV negative women. It is unknown whether the incidence of PPH is higher in HIV positive women; and/or whether HIV positive women have more severe bleeding and suffer greater morbidity as a result of PPH. The aim of the study was to investigate the effect of HIV infection on the incidence and severity of PPH. All women delivering at Mowbray Maternity and Groote Schuur Hospital in 2009 who had PPH were identified through a manual search of labour ward and operating theatre records. The women were categorized according to their HIV status as HIV positive, negative and untested. Data was also obtained on HIV status of the whole delivery population at these two hospitals. For women with PPH, data regarding background characteristics:- blood loss; cause of PPH and management provided; severity of and morbidity from PPH was analysed by comparing the HIV positive with the HIV negative group. Severity was assessed in terms of blood loss alone. Morbidity on the other hand was a composite assessment of blood loss, need for blood products, interventions required and complications of the PPH. Data was also collected on CD4 counts and treatment provided although the study was not powered to investigate these factors as associations.","abstract_has_math":false,"creators":["Chilopora, Garvey Chipiliro"],"institution":"Department of Obstetrics and Gynaecology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Fawcus, Susan R"],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012","date_published":"2012","updated_at":"2026-07-22T22:23:22Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/3036","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Fawcus, Susan R"]},{"key":"dc:creator","label":"Author","values":["Chilopora, Garvey Chipiliro"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-07-28T14:48:29Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-07-28T14:48:29Z"]},{"key":"dc:date.issued","label":"Date","values":["2012"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Obstetrics and Gynaecology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MPhil"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/3036"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Includes abstract.","Includes bibliographical references."]},{"key":"dc:description.abstract","label":"Abstract","values":["Postpartum haemorrhage (PPH) accounts for more than 75% of maternal deaths from obstetric haemorrhage. In South Africa, maternal mortality resulting from postpartum haemorrhage has persistently been shown to be higher in HIV positive compared to HIV negative women. It is unknown whether the incidence of PPH is higher in HIV positive women; and/or whether HIV positive women have more severe bleeding and suffer greater morbidity as a result of PPH. The aim of the study was to investigate the effect of HIV infection on the incidence and severity of PPH. All women delivering at Mowbray Maternity and Groote Schuur Hospital in 2009 who had PPH were identified through a manual search of labour ward and operating theatre records. The women were categorized according to their HIV status as HIV positive, negative and untested. Data was also obtained on HIV status of the whole delivery population at these two hospitals. For women with PPH, data regarding background characteristics:- blood loss; cause of PPH and management provided; severity of and morbidity from PPH was analysed by comparing the HIV positive with the HIV negative group. Severity was assessed in terms of blood loss alone. Morbidity on the other hand was a composite assessment of blood loss, need for blood products, interventions required and complications of the PPH. Data was also collected on CD4 counts and treatment provided although the study was not powered to investigate these factors as associations."]},{"key":"dc:title","label":"Title","values":["The effect of HIV infection on the incidence and severity of post-partum haemorrhage"]}]}],"canonical_facts":{"dc:contributor.advisor":["Fawcus, Susan R"],"dc:creator":["Chilopora, Garvey Chipiliro"],"dc:date.accessioned":["2014-07-28T14:48:29Z"],"dc:date.available":["2014-07-28T14:48:29Z"],"dc:date.issued":["2012"],"dc:description":["Includes abstract.","Includes bibliographical references."],"dc:description.abstract":["Postpartum haemorrhage (PPH) accounts for more than 75% of maternal deaths from obstetric haemorrhage. In South Africa, maternal mortality resulting from postpartum haemorrhage has persistently been shown to be higher in HIV positive compared to HIV negative women. It is unknown whether the incidence of PPH is higher in HIV positive women; and/or whether HIV positive women have more severe bleeding and suffer greater morbidity as a result of PPH. The aim of the study was to investigate the effect of HIV infection on the incidence and severity of PPH. All women delivering at Mowbray Maternity and Groote Schuur Hospital in 2009 who had PPH were identified through a manual search of labour ward and operating theatre records. The women were categorized according to their HIV status as HIV positive, negative and untested. Data was also obtained on HIV status of the whole delivery population at these two hospitals. For women with PPH, data regarding background characteristics:- blood loss; cause of PPH and management provided; severity of and morbidity from PPH was analysed by comparing the HIV positive with the HIV negative group. Severity was assessed in terms of blood loss alone. Morbidity on the other hand was a composite assessment of blood loss, need for blood products, interventions required and complications of the PPH. Data was also collected on CD4 counts and treatment provided although the study was not powered to investigate these factors as associations."],"dc:identifier.uri":["http://hdl.handle.net/11427/3036"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Obstetrics and Gynaecology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["The effect of HIV infection on the incidence and severity of post-partum haemorrhage"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MPhil"]},"updated_at":"2026-07-22T22:23:22Z"}