{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/2788"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/2788","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Utility of newer and novel technologies for the diagnosis and treatment-monitoring of tuberculosis using different biological fluids","abstract":"Smear microscopy has a poor sensitivity, cannot identify drug resistance, and when followed up with culture tests it takes several weeks to obtain a result. Furthermore, sputum-scarce and smear negative tuberculosis is difficult to diagnose. The use of biological samples other than sputum such as blood, urine and bronchoalveolar lavage fluid, are thus increasingly being used for diagnostic purposes. However, there is a low yield of rapid diagnostic tools, and the use of recently released commercially available technologies for tuberculosis diagnosis requires clarification.","abstract_html":"Smear microscopy has a poor sensitivity, cannot identify drug resistance, and when followed up with culture tests it takes several weeks to obtain a result. Furthermore, sputum-scarce and smear negative tuberculosis is difficult to diagnose. The use of biological samples other than sputum such as blood, urine and bronchoalveolar lavage fluid, are thus increasingly being used for diagnostic purposes. However, there is a low yield of rapid diagnostic tools, and the use of recently released commercially available technologies for tuberculosis diagnosis requires clarification.","abstract_has_math":false,"creators":["Lenders, Laura Mary"],"institution":"Division of Pulmonology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Dheda, Keertan"],"committee_chairs":[],"committee_members":[],"year":2010,"date_issued":"2010","date_published":"2010","updated_at":"2026-07-22T22:22:42Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/2788","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Dheda, Keertan"]},{"key":"dc:creator","label":"Author","values":["Lenders, Laura Mary"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-07-28T11:01:47Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-07-28T11:01:47Z"]},{"key":"dc:date.issued","label":"Date","values":["2010"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Division of Pulmonology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MSc"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/2788"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Includes abstract.","Includes bibliographical references (leaves 127-145)."]},{"key":"dc:description.abstract","label":"Abstract","values":["Smear microscopy has a poor sensitivity, cannot identify drug resistance, and when followed up with culture tests it takes several weeks to obtain a result. Furthermore, sputum-scarce and smear negative tuberculosis is difficult to diagnose. The use of biological samples other than sputum such as blood, urine and bronchoalveolar lavage fluid, are thus increasingly being used for diagnostic purposes. However, there is a low yield of rapid diagnostic tools, and the use of recently released commercially available technologies for tuberculosis diagnosis requires clarification."]},{"key":"dc:title","label":"Title","values":["Utility of newer and novel technologies for the diagnosis and treatment-monitoring of tuberculosis using different biological fluids"]}]}],"canonical_facts":{"dc:contributor.advisor":["Dheda, Keertan"],"dc:creator":["Lenders, Laura Mary"],"dc:date.accessioned":["2014-07-28T11:01:47Z"],"dc:date.available":["2014-07-28T11:01:47Z"],"dc:date.issued":["2010"],"dc:description":["Includes abstract.","Includes bibliographical references (leaves 127-145)."],"dc:description.abstract":["Smear microscopy has a poor sensitivity, cannot identify drug resistance, and when followed up with culture tests it takes several weeks to obtain a result. Furthermore, sputum-scarce and smear negative tuberculosis is difficult to diagnose. The use of biological samples other than sputum such as blood, urine and bronchoalveolar lavage fluid, are thus increasingly being used for diagnostic purposes. However, there is a low yield of rapid diagnostic tools, and the use of recently released commercially available technologies for tuberculosis diagnosis requires clarification."],"dc:identifier.uri":["http://hdl.handle.net/11427/2788"],"dc:language.iso":["eng"],"dc:publisher.department":["Division of Pulmonology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["Utility of newer and novel technologies for the diagnosis and treatment-monitoring of tuberculosis using different biological fluids"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MSc"]},"updated_at":"2026-07-22T22:22:42Z"}