{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/2704"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/2704","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Expression and purification of HGXPRT from Plasmodium falciparum and characterisation of its interaction with an effector chalcone","abstract":"The aim of this study was to express and purify PƒHGXPRT and to explore three techniques, namely gel filtration HPLC, photolabelling, and Isothermal Titration Calorimetry (ITC) for ultimately characterising the interaction of the effector chalcones with the protein.","abstract_html":"The aim of this study was to express and purify PƒHGXPRT and to explore three techniques, namely gel filtration HPLC, photolabelling, and Isothermal Titration Calorimetry (ITC) for ultimately characterising the interaction of the effector chalcones with the protein.","abstract_has_math":false,"creators":["Van der Bergh, Naadia"],"institution":"Division of Chemical Pathology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["McIntosh, David B"],"committee_chairs":[],"committee_members":[],"year":2008,"date_issued":"2008","date_published":"2008","updated_at":"2026-07-22T22:23:31Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/2704","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["McIntosh, David B"]},{"key":"dc:creator","label":"Author","values":["Van der Bergh, Naadia"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-07-28T08:15:50Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-07-28T08:15:50Z"]},{"key":"dc:date.issued","label":"Date","values":["2008"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Division of Chemical Pathology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MSc"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/2704"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Includes bibliographical references (leaves 90-103)."]},{"key":"dc:description.abstract","label":"Abstract","values":["The aim of this study was to express and purify PƒHGXPRT and to explore three techniques, namely gel filtration HPLC, photolabelling, and Isothermal Titration Calorimetry (ITC) for ultimately characterising the interaction of the effector chalcones with the protein."]},{"key":"dc:title","label":"Title","values":["Expression and purification of HGXPRT from Plasmodium falciparum and characterisation of its interaction with an effector chalcone"]}]}],"canonical_facts":{"dc:contributor.advisor":["McIntosh, David B"],"dc:creator":["Van der Bergh, Naadia"],"dc:date.accessioned":["2014-07-28T08:15:50Z"],"dc:date.available":["2014-07-28T08:15:50Z"],"dc:date.issued":["2008"],"dc:description":["Includes bibliographical references (leaves 90-103)."],"dc:description.abstract":["The aim of this study was to express and purify PƒHGXPRT and to explore three techniques, namely gel filtration HPLC, photolabelling, and Isothermal Titration Calorimetry (ITC) for ultimately characterising the interaction of the effector chalcones with the protein."],"dc:identifier.uri":["http://hdl.handle.net/11427/2704"],"dc:language.iso":["eng"],"dc:publisher.department":["Division of Chemical Pathology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["Expression and purification of HGXPRT from Plasmodium falciparum and characterisation of its interaction with an effector chalcone"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MSc"]},"updated_at":"2026-07-22T22:23:31Z"}