{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/26994"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/26994","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Theoretical and technical aspects of using the Doppler umbilical flow waveform to assess compromised foetal circulation","abstract":"The aim of this thesis was to investigate the feasibility of using the shape of the umbilical flow waveform, obtained clinically with Doppler ultrasound, to monitor the condition growth impaired foetuses. This aim was addressed via the following . 1. Survey the literature to obtain information regarding : a) the foetal blood flow distribution for normal foetuses. b) the effect of placental pathology and maternal hyperoxygenation in compromised foetuses. 2. Model the foetal circulation to investigate the effect, on the umbilical flow waveform, of physiological changes resulting from placental insufficiency. 3. Perform a theoretical and practical assessment of Doppler ultrasound by considering its suitability in monitoring foetal condition, through alterations in the umbilical blood flow waveform shape. 4. Clinically gather and analyse umbilical blood flow waveforms from foetuses currently on a trial to investigate appropriate protocols for the assessment of maternal hyperoxygenation.","abstract_html":"The aim of this thesis was to investigate the feasibility of using the shape of the umbilical flow waveform, obtained clinically with Doppler ultrasound, to monitor the condition growth impaired foetuses. This aim was addressed via the following . 1. Survey the literature to obtain information regarding : a) the foetal blood flow distribution for normal foetuses. b) the effect of placental pathology and maternal hyperoxygenation in compromised foetuses. 2. Model the foetal circulation to investigate the effect, on the umbilical flow waveform, of physiological changes resulting from placental insufficiency. 3. Perform a theoretical and practical assessment of Doppler ultrasound by considering its suitability in monitoring foetal condition, through alterations in the umbilical blood flow waveform shape. 4. Clinically gather and analyse umbilical blood flow waveforms from foetuses currently on a trial to investigate appropriate protocols for the assessment of maternal hyperoxygenation.","abstract_has_math":false,"creators":["Cowper, John Guy"],"institution":"Department of Human Biology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Capper, Wayne"],"committee_chairs":[],"committee_members":[],"year":1996,"date_issued":"1996","date_published":"1996","updated_at":"2026-07-22T22:22:42Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/26994","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Capper, Wayne"]},{"key":"dc:creator","label":"Author","values":["Cowper, John Guy"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2018-01-25T13:59:52Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2018-01-25T13:59:52Z"]},{"key":"dc:date.issued","label":"Date","values":["1996"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Human Biology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MSc (Med)"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/26994"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Includes bibliography."]},{"key":"dc:description.abstract","label":"Abstract","values":["The aim of this thesis was to investigate the feasibility of using the shape of the umbilical flow waveform, obtained clinically with Doppler ultrasound, to monitor the condition growth impaired foetuses. This aim was addressed via the following . 1. Survey the literature to obtain information regarding : a) the foetal blood flow distribution for normal foetuses. b) the effect of placental pathology and maternal hyperoxygenation in compromised foetuses. 2. Model the foetal circulation to investigate the effect, on the umbilical flow waveform, of physiological changes resulting from placental insufficiency. 3. Perform a theoretical and practical assessment of Doppler ultrasound by considering its suitability in monitoring foetal condition, through alterations in the umbilical blood flow waveform shape. 4. Clinically gather and analyse umbilical blood flow waveforms from foetuses currently on a trial to investigate appropriate protocols for the assessment of maternal hyperoxygenation."]},{"key":"dc:title","label":"Title","values":["Theoretical and technical aspects of using the Doppler umbilical flow waveform to assess compromised foetal circulation"]}]}],"canonical_facts":{"dc:contributor.advisor":["Capper, Wayne"],"dc:creator":["Cowper, John Guy"],"dc:date.accessioned":["2018-01-25T13:59:52Z"],"dc:date.available":["2018-01-25T13:59:52Z"],"dc:date.issued":["1996"],"dc:description":["Includes bibliography."],"dc:description.abstract":["The aim of this thesis was to investigate the feasibility of using the shape of the umbilical flow waveform, obtained clinically with Doppler ultrasound, to monitor the condition growth impaired foetuses. This aim was addressed via the following . 1. Survey the literature to obtain information regarding : a) the foetal blood flow distribution for normal foetuses. b) the effect of placental pathology and maternal hyperoxygenation in compromised foetuses. 2. Model the foetal circulation to investigate the effect, on the umbilical flow waveform, of physiological changes resulting from placental insufficiency. 3. Perform a theoretical and practical assessment of Doppler ultrasound by considering its suitability in monitoring foetal condition, through alterations in the umbilical blood flow waveform shape. 4. Clinically gather and analyse umbilical blood flow waveforms from foetuses currently on a trial to investigate appropriate protocols for the assessment of maternal hyperoxygenation."],"dc:identifier.uri":["http://hdl.handle.net/11427/26994"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Human Biology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["Theoretical and technical aspects of using the Doppler umbilical flow waveform to assess compromised foetal circulation"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MSc (Med)"]},"updated_at":"2026-07-22T22:22:42Z"}