{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/22184"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/22184","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"The production of Y-linolenic acid by Choanephora curcubitarum","abstract":"Gamma linolenic acid (GLA) is an essential fatty acid which has been shown to be beneficial for a large number of diseases. At present the fatty acid is marketed as a health product and the prime source of GLA is the evening primrose flower. There are several problems associated with producing the oil and as there is a growing demand for GLA for pharmaceutical and clinical applications, alternative sources are being sought. Choanephora curcubitarum is known to produce GLA and the production of GLA by fermentation of this organism has been successfully achieved by National Chemical Products. The ultimate aim of this project is to genetically manipulate this organism in order to increase the yields of GLA. Tn this thesis the basic groundwork needed to develop a genetic system in C. curcubitarum has been covered.","abstract_html":"Gamma linolenic acid (GLA) is an essential fatty acid which has been shown to be beneficial for a large number of diseases. At present the fatty acid is marketed as a health product and the prime source of GLA is the evening primrose flower. There are several problems associated with producing the oil and as there is a growing demand for GLA for pharmaceutical and clinical applications, alternative sources are being sought. Choanephora curcubitarum is known to produce GLA and the production of GLA by fermentation of this organism has been successfully achieved by National Chemical Products. The ultimate aim of this project is to genetically manipulate this organism in order to increase the yields of GLA. Tn this thesis the basic groundwork needed to develop a genetic system in C. curcubitarum has been covered.","abstract_has_math":false,"creators":["Dry, Carol Jayne"],"institution":"Department of Molecular and Cell Biology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Woods, David R"],"committee_chairs":[],"committee_members":[],"year":1985,"date_issued":"1985","date_published":"1985","updated_at":"2026-07-22T22:22:46Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/22184","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Woods, David R"]},{"key":"dc:creator","label":"Author","values":["Dry, Carol Jayne"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2016-10-19T03:55:37Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2016-10-19T03:55:37Z"]},{"key":"dc:date.issued","label":"Date","values":["1985"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Molecular and Cell Biology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MSc"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/22184"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Bibliography: pages 158-164."]},{"key":"dc:description.abstract","label":"Abstract","values":["Gamma linolenic acid (GLA) is an essential fatty acid which has been shown to be beneficial for a large number of diseases. At present the fatty acid is marketed as a health product and the prime source of GLA is the evening primrose flower. There are several problems associated with producing the oil and as there is a growing demand for GLA for pharmaceutical and clinical applications, alternative sources are being sought. Choanephora curcubitarum is known to produce GLA and the production of GLA by fermentation of this organism has been successfully achieved by National Chemical Products. The ultimate aim of this project is to genetically manipulate this organism in order to increase the yields of GLA. Tn this thesis the basic groundwork needed to develop a genetic system in C. curcubitarum has been covered."]},{"key":"dc:title","label":"Title","values":["The production of Y-linolenic acid by Choanephora curcubitarum"]}]}],"canonical_facts":{"dc:contributor.advisor":["Woods, David R"],"dc:creator":["Dry, Carol Jayne"],"dc:date.accessioned":["2016-10-19T03:55:37Z"],"dc:date.available":["2016-10-19T03:55:37Z"],"dc:date.issued":["1985"],"dc:description":["Bibliography: pages 158-164."],"dc:description.abstract":["Gamma linolenic acid (GLA) is an essential fatty acid which has been shown to be beneficial for a large number of diseases. At present the fatty acid is marketed as a health product and the prime source of GLA is the evening primrose flower. There are several problems associated with producing the oil and as there is a growing demand for GLA for pharmaceutical and clinical applications, alternative sources are being sought. Choanephora curcubitarum is known to produce GLA and the production of GLA by fermentation of this organism has been successfully achieved by National Chemical Products. The ultimate aim of this project is to genetically manipulate this organism in order to increase the yields of GLA. Tn this thesis the basic groundwork needed to develop a genetic system in C. curcubitarum has been covered."],"dc:identifier.uri":["http://hdl.handle.net/11427/22184"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Molecular and Cell Biology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["The production of Y-linolenic acid by Choanephora curcubitarum"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MSc"]},"updated_at":"2026-07-22T22:22:46Z"}