{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/21500"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/21500","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Studies on growth, modelling and pigment production by the yeast Phaffia rhodozyma","abstract":"Within the aquaculture industry a potential has been identified for the pigment astaxanthin. Astaxanthin is the carotenoid responsible for the distinctive coloration of salmonids, crustaceans and certain birds. Due to the fact that animals cannot synthesize carotenoids themselves, it is necessary for these pigments to be present in their food source. In the case of farm-raised salmonids and crustaceans, supplementation of their food with astaxanthin is required. The chemical synthesis of astaxanthin is very costly and complicated. As a result natural, microbial sources of astaxanthin are being investigated. Phaffia rhodozyma is the only yeast known to synthesize astaxanthin as its principle carotenoid. The aim of this dissertation is to present a study investigating the growth and pigmentation of P. rhodozyma, with a view to its commercial production. A P. rhodozyma mutant (UCT-1 N-3693) with a 50% increased total carotenoid content was selected after NTG mutagenesis of the wild strain.","abstract_html":"Within the aquaculture industry a potential has been identified for the pigment astaxanthin. Astaxanthin is the carotenoid responsible for the distinctive coloration of salmonids, crustaceans and certain birds. Due to the fact that animals cannot synthesize carotenoids themselves, it is necessary for these pigments to be present in their food source. In the case of farm-raised salmonids and crustaceans, supplementation of their food with astaxanthin is required. The chemical synthesis of astaxanthin is very costly and complicated. As a result natural, microbial sources of astaxanthin are being investigated. Phaffia rhodozyma is the only yeast known to synthesize astaxanthin as its principle carotenoid. The aim of this dissertation is to present a study investigating the growth and pigmentation of P. rhodozyma, with a view to its commercial production. A P. rhodozyma mutant (UCT-1 N-3693) with a 50% increased total carotenoid content was selected after NTG mutagenesis of the wild strain.","abstract_has_math":false,"creators":["Reynders, Michael Barry"],"institution":"Centre for Bioprocess Engineering Research","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Harrison, STL","Rawlings, D E"],"committee_chairs":[],"committee_members":[],"year":1995,"date_issued":"1995","date_published":"1995","updated_at":"2026-07-22T22:22:51Z","subjects":["Bioprocess Engineering"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/21500","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Harrison, STL","Rawlings, D E"]},{"key":"dc:creator","label":"Author","values":["Reynders, Michael Barry"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2016-08-24T12:55:12Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2016-08-24T12:55:12Z"]},{"key":"dc:date.issued","label":"Date","values":["1995"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Centre for Bioprocess Engineering Research"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MSc (Eng)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Bioprocess Engineering"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/21500"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Bibliography: pages 117-123."]},{"key":"dc:description.abstract","label":"Abstract","values":["Within the aquaculture industry a potential has been identified for the pigment astaxanthin. Astaxanthin is the carotenoid responsible for the distinctive coloration of salmonids, crustaceans and certain birds. Due to the fact that animals cannot synthesize carotenoids themselves, it is necessary for these pigments to be present in their food source. In the case of farm-raised salmonids and crustaceans, supplementation of their food with astaxanthin is required. The chemical synthesis of astaxanthin is very costly and complicated. As a result natural, microbial sources of astaxanthin are being investigated. Phaffia rhodozyma is the only yeast known to synthesize astaxanthin as its principle carotenoid. The aim of this dissertation is to present a study investigating the growth and pigmentation of P. rhodozyma, with a view to its commercial production. A P. rhodozyma mutant (UCT-1 N-3693) with a 50% increased total carotenoid content was selected after NTG mutagenesis of the wild strain."]},{"key":"dc:title","label":"Title","values":["Studies on growth, modelling and pigment production by the yeast Phaffia rhodozyma"]}]}],"canonical_facts":{"dc:contributor.advisor":["Harrison, STL","Rawlings, D E"],"dc:creator":["Reynders, Michael Barry"],"dc:date.accessioned":["2016-08-24T12:55:12Z"],"dc:date.available":["2016-08-24T12:55:12Z"],"dc:date.issued":["1995"],"dc:description":["Bibliography: pages 117-123."],"dc:description.abstract":["Within the aquaculture industry a potential has been identified for the pigment astaxanthin. Astaxanthin is the carotenoid responsible for the distinctive coloration of salmonids, crustaceans and certain birds. Due to the fact that animals cannot synthesize carotenoids themselves, it is necessary for these pigments to be present in their food source. In the case of farm-raised salmonids and crustaceans, supplementation of their food with astaxanthin is required. The chemical synthesis of astaxanthin is very costly and complicated. As a result natural, microbial sources of astaxanthin are being investigated. Phaffia rhodozyma is the only yeast known to synthesize astaxanthin as its principle carotenoid. The aim of this dissertation is to present a study investigating the growth and pigmentation of P. rhodozyma, with a view to its commercial production. A P. rhodozyma mutant (UCT-1 N-3693) with a 50% increased total carotenoid content was selected after NTG mutagenesis of the wild strain."],"dc:identifier.uri":["http://hdl.handle.net/11427/21500"],"dc:language.iso":["eng"],"dc:publisher.department":["Centre for Bioprocess Engineering Research"],"dc:publisher.institution":["University of Cape Town"],"dc:subject":["Bioprocess Engineering"],"dc:title":["Studies on growth, modelling and pigment production by the yeast Phaffia rhodozyma"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MSc (Eng)"]},"updated_at":"2026-07-22T22:22:51Z"}