{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/21498"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/21498","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"The primary structures and the evolutionary consequences of the olisthodiscus luteus histone proteins","abstract":"During the course of this study, the histones of the algae Olisthodiscus luteus were isolated, purified and fractionated. Identification of the histones was achieved by partial primary structure analysis. The histones Hl, H2A, H2B, H3 and H4 were found to be present in the O. luteus nucleus. The complete structure of H2A and H4 was determined. There is no evidence of the existence of the unique histone HO1 (Rizzo et al., 1985). Construction of phylogenetic trees suggests that the alga Olisthodiscus luteus diverged from the animal line. By sequence comparison, the most closely related histone sequence to the algae was found to be that of the echinodermata. An endosymbiotic event between an echinodermata ancestor and a primitive unicellular alga is hypothesised in an attempt to explain the smilarity between the histones.","abstract_html":"During the course of this study, the histones of the algae Olisthodiscus luteus were isolated, purified and fractionated. Identification of the histones was achieved by partial primary structure analysis. The histones Hl, H2A, H2B, H3 and H4 were found to be present in the O. luteus nucleus. The complete structure of H2A and H4 was determined. There is no evidence of the existence of the unique histone HO1 (Rizzo et al., 1985). Construction of phylogenetic trees suggests that the alga Olisthodiscus luteus diverged from the animal line. By sequence comparison, the most closely related histone sequence to the algae was found to be that of the echinodermata. An endosymbiotic event between an echinodermata ancestor and a primitive unicellular alga is hypothesised in an attempt to explain the smilarity between the histones.","abstract_has_math":false,"creators":["Spit, Anthony"],"institution":"Department of Molecular and Cell Biology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Brandt, Wolf F"],"committee_chairs":[],"committee_members":[],"year":1993,"date_issued":"1993","date_published":"1993","updated_at":"2026-07-22T22:23:47Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/21498","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Brandt, Wolf F"]},{"key":"dc:creator","label":"Author","values":["Spit, Anthony"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2016-08-24T12:54:14Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2016-08-24T12:54:14Z"]},{"key":"dc:date.issued","label":"Date","values":["1993"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Molecular and Cell Biology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Doctoral Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["PhD"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/21498"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Bibliography: pages 187-194."]},{"key":"dc:description.abstract","label":"Abstract","values":["During the course of this study, the histones of the algae Olisthodiscus luteus were isolated, purified and fractionated. Identification of the histones was achieved by partial primary structure analysis. The histones Hl, H2A, H2B, H3 and H4 were found to be present in the O. luteus nucleus. The complete structure of H2A and H4 was determined. There is no evidence of the existence of the unique histone HO1 (Rizzo et al., 1985). Construction of phylogenetic trees suggests that the alga Olisthodiscus luteus diverged from the animal line. By sequence comparison, the most closely related histone sequence to the algae was found to be that of the echinodermata. An endosymbiotic event between an echinodermata ancestor and a primitive unicellular alga is hypothesised in an attempt to explain the smilarity between the histones."]},{"key":"dc:title","label":"Title","values":["The primary structures and the evolutionary consequences of the olisthodiscus luteus histone proteins"]}]}],"canonical_facts":{"dc:contributor.advisor":["Brandt, Wolf F"],"dc:creator":["Spit, Anthony"],"dc:date.accessioned":["2016-08-24T12:54:14Z"],"dc:date.available":["2016-08-24T12:54:14Z"],"dc:date.issued":["1993"],"dc:description":["Bibliography: pages 187-194."],"dc:description.abstract":["During the course of this study, the histones of the algae Olisthodiscus luteus were isolated, purified and fractionated. Identification of the histones was achieved by partial primary structure analysis. The histones Hl, H2A, H2B, H3 and H4 were found to be present in the O. luteus nucleus. The complete structure of H2A and H4 was determined. There is no evidence of the existence of the unique histone HO1 (Rizzo et al., 1985). Construction of phylogenetic trees suggests that the alga Olisthodiscus luteus diverged from the animal line. By sequence comparison, the most closely related histone sequence to the algae was found to be that of the echinodermata. An endosymbiotic event between an echinodermata ancestor and a primitive unicellular alga is hypothesised in an attempt to explain the smilarity between the histones."],"dc:identifier.uri":["http://hdl.handle.net/11427/21498"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Molecular and Cell Biology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["The primary structures and the evolutionary consequences of the olisthodiscus luteus histone proteins"],"dc:type":["Doctoral Thesis"],"dc:type.qualificationlevel":["Doctoral"],"dc:type.qualificationname":["PhD"]},"updated_at":"2026-07-22T22:23:47Z"}