{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/20297"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/20297","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"A review of children admitted to a regional hospital in Cape Town with community acquired pneumonia","abstract":"Background: Pneumonia is a leading cause of death in children under - five. Epidemiology in our province at regional level has not been described since 2004, when HAART was rolled out and pneumococcal conjugate vaccination (PCV) was introduced. Objectives: Describe the demographic profile, disease severity, risks for transfer and mortality and the management of children >2 months, admitted with CAP over a one year period. Methods: Retrospective descriptive study of every second patient (>2 months to 13 years) admitted to Somerset Hospital in 2012 with the diagnosis of CAP. Demographic, clinical and outcome data were extracted from hospital records and analysed using STATA®. Results: Of 380 cases reviewed, 90% had severe disease; the median age was 9.4 months (IQR 4.8 - 23). Of these 89 (23%) were LBW (<2500g) and 75 (20%) were born premature. Median age at presentation for these groups was 5.7 months compared with 10.6 months in t erm children ( p=0.0003 ). Forty - one (12%) were severely malnourished; 34 (9%) were HIV - positive. Children below 1 0 /12 were more likely to have incomplete immunisations (57/190, p=0.011). Only 15% of TB - exposed children < 5 years were on Isoniazid Prevention Therapy (IPT). Prevalence of comorbid conditions was high. Median duration of stay was 3 days (IQR 2 - 6); this increased to 6.5 (IQR 4.5 - 9.5) with neurological disease and 6 (IQR4 - 10) with proven RSV. Seventeen patients (4.5%) required transfer to tertiary level. Mortality rate was 0.5%. Conclusion: Preventative measures must focus on populations at risk - LBW and preterm children in first year of life, malnourished children and those with comorbidities like HIV. Immunisation and IPT rates can be improved.","abstract_html":"Background: Pneumonia is a leading cause of death in children under - five. Epidemiology in our province at regional level has not been described since 2004, when HAART was rolled out and pneumococcal conjugate vaccination (PCV) was introduced. Objectives: Describe the demographic profile, disease severity, risks for transfer and mortality and the management of children &gt;2 months, admitted with CAP over a one year period. Methods: Retrospective descriptive study of every second patient (&gt;2 months to 13 years) admitted to Somerset Hospital in 2012 with the diagnosis of CAP. Demographic, clinical and outcome data were extracted from hospital records and analysed using STATA®. Results: Of 380 cases reviewed, 90% had severe disease; the median age was 9.4 months (IQR 4.8 - 23). Of these 89 (23%) were LBW (&lt;2500g) and 75 (20%) were born premature. Median age at presentation for these groups was 5.7 months compared with 10.6 months in t erm children ( p=0.0003 ). Forty - one (12%) were severely malnourished; 34 (9%) were HIV - positive. Children below 1 0 /12 were more likely to have incomplete immunisations (57/190, p=0.011). Only 15% of TB - exposed children &lt; 5 years were on Isoniazid Prevention Therapy (IPT). Prevalence of comorbid conditions was high. Median duration of stay was 3 days (IQR 2 - 6); this increased to 6.5 (IQR 4.5 - 9.5) with neurological disease and 6 (IQR4 - 10) with proven RSV. Seventeen patients (4.5%) required transfer to tertiary level. Mortality rate was 0.5%. Conclusion: Preventative measures must focus on populations at risk - LBW and preterm children in first year of life, malnourished children and those with comorbidities like HIV. Immunisation and IPT rates can be improved.","abstract_has_math":false,"creators":["Meyer, Mandy-Lyn"],"institution":"Department of Paediatrics and Child Health","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Cooke, M L"],"committee_chairs":[],"committee_members":[],"year":2016,"date_issued":"2016","date_published":"2016","updated_at":"2026-07-22T22:23:44Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/20297","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Cooke, M L"]},{"key":"dc:creator","label":"Author","values":["Meyer, Mandy-Lyn"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2016-07-11T13:50:59Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2016-07-11T13:50:59Z"]},{"key":"dc:date.issued","label":"Date","values":["2016"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Paediatrics and Child Health"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MMed"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/20297"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Background: Pneumonia is a leading cause of death in children under - five. Epidemiology in our province at regional level has not been described since 2004, when HAART was rolled out and pneumococcal conjugate vaccination (PCV) was introduced. Objectives: Describe the demographic profile, disease severity, risks for transfer and mortality and the management of children >2 months, admitted with CAP over a one year period. Methods: Retrospective descriptive study of every second patient (>2 months to 13 years) admitted to Somerset Hospital in 2012 with the diagnosis of CAP. Demographic, clinical and outcome data were extracted from hospital records and analysed using STATA®. Results: Of 380 cases reviewed, 90% had severe disease; the median age was 9.4 months (IQR 4.8 - 23). Of these 89 (23%) were LBW (<2500g) and 75 (20%) were born premature. Median age at presentation for these groups was 5.7 months compared with 10.6 months in t erm children ( p=0.0003 ). Forty - one (12%) were severely malnourished; 34 (9%) were HIV - positive. Children below 1 0 /12 were more likely to have incomplete immunisations (57/190, p=0.011). Only 15% of TB - exposed children < 5 years were on Isoniazid Prevention Therapy (IPT). Prevalence of comorbid conditions was high. Median duration of stay was 3 days (IQR 2 - 6); this increased to 6.5 (IQR 4.5 - 9.5) with neurological disease and 6 (IQR4 - 10) with proven RSV. Seventeen patients (4.5%) required transfer to tertiary level. Mortality rate was 0.5%. Conclusion: Preventative measures must focus on populations at risk - LBW and preterm children in first year of life, malnourished children and those with comorbidities like HIV. Immunisation and IPT rates can be improved."]},{"key":"dc:title","label":"Title","values":["A review of children admitted to a regional hospital in Cape Town with community acquired pneumonia"]}]}],"canonical_facts":{"dc:contributor.advisor":["Cooke, M L"],"dc:creator":["Meyer, Mandy-Lyn"],"dc:date.accessioned":["2016-07-11T13:50:59Z"],"dc:date.available":["2016-07-11T13:50:59Z"],"dc:date.issued":["2016"],"dc:description.abstract":["Background: Pneumonia is a leading cause of death in children under - five. Epidemiology in our province at regional level has not been described since 2004, when HAART was rolled out and pneumococcal conjugate vaccination (PCV) was introduced. Objectives: Describe the demographic profile, disease severity, risks for transfer and mortality and the management of children >2 months, admitted with CAP over a one year period. Methods: Retrospective descriptive study of every second patient (>2 months to 13 years) admitted to Somerset Hospital in 2012 with the diagnosis of CAP. Demographic, clinical and outcome data were extracted from hospital records and analysed using STATA®. Results: Of 380 cases reviewed, 90% had severe disease; the median age was 9.4 months (IQR 4.8 - 23). Of these 89 (23%) were LBW (<2500g) and 75 (20%) were born premature. Median age at presentation for these groups was 5.7 months compared with 10.6 months in t erm children ( p=0.0003 ). Forty - one (12%) were severely malnourished; 34 (9%) were HIV - positive. Children below 1 0 /12 were more likely to have incomplete immunisations (57/190, p=0.011). Only 15% of TB - exposed children < 5 years were on Isoniazid Prevention Therapy (IPT). Prevalence of comorbid conditions was high. Median duration of stay was 3 days (IQR 2 - 6); this increased to 6.5 (IQR 4.5 - 9.5) with neurological disease and 6 (IQR4 - 10) with proven RSV. Seventeen patients (4.5%) required transfer to tertiary level. Mortality rate was 0.5%. Conclusion: Preventative measures must focus on populations at risk - LBW and preterm children in first year of life, malnourished children and those with comorbidities like HIV. Immunisation and IPT rates can be improved."],"dc:identifier.uri":["http://hdl.handle.net/11427/20297"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Paediatrics and Child Health"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["A review of children admitted to a regional hospital in Cape Town with community acquired pneumonia"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MMed"]},"updated_at":"2026-07-22T22:23:44Z"}