{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/16971"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/16971","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Physicochemical and immunological studies of thermally induced conformational changes in protein antigens of mycobacterium bovis strain, BCG","abstract":"In this study the conformational changes in beat stable and heat labile protein immunoprecipitin antigens of a typical mycobacterin, the culture filtrate of Mycobacterium bovis, strain BCG 172, during heating and cooling have been investigated and related to the more obvious manifestations of thermal denaturation which have been reported from studies of heated mycobacterins.","abstract_html":"In this study the conformational changes in beat stable and heat labile protein immunoprecipitin antigens of a typical mycobacterin, the culture filtrate of Mycobacterium bovis, strain BCG 172, during heating and cooling have been investigated and related to the more obvious manifestations of thermal denaturation which have been reported from studies of heated mycobacterins.","abstract_has_math":false,"creators":["Harpur, David Patrick"],"institution":"Department of Molecular and Cell Biology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1981,"date_issued":"1981","date_published":"1981","updated_at":"2026-07-22T22:22:38Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/16971","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Harpur, David Patrick"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2016-02-12T07:06:03Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2016-02-12T07:06:03Z"]},{"key":"dc:date.issued","label":"Date","values":["1981"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Molecular and Cell Biology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Doctoral Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["PhD"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/16971"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Bibliography: pages 147-155."]},{"key":"dc:description.abstract","label":"Abstract","values":["In this study the conformational changes in beat stable and heat labile protein immunoprecipitin antigens of a typical mycobacterin, the culture filtrate of Mycobacterium bovis, strain BCG 172, during heating and cooling have been investigated and related to the more obvious manifestations of thermal denaturation which have been reported from studies of heated mycobacterins."]},{"key":"dc:title","label":"Title","values":["Physicochemical and immunological studies of thermally induced conformational changes in protein antigens of mycobacterium bovis strain, BCG"]}]}],"canonical_facts":{"dc:creator":["Harpur, David Patrick"],"dc:date.accessioned":["2016-02-12T07:06:03Z"],"dc:date.available":["2016-02-12T07:06:03Z"],"dc:date.issued":["1981"],"dc:description":["Bibliography: pages 147-155."],"dc:description.abstract":["In this study the conformational changes in beat stable and heat labile protein immunoprecipitin antigens of a typical mycobacterin, the culture filtrate of Mycobacterium bovis, strain BCG 172, during heating and cooling have been investigated and related to the more obvious manifestations of thermal denaturation which have been reported from studies of heated mycobacterins."],"dc:identifier.uri":["http://hdl.handle.net/11427/16971"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Molecular and Cell Biology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["Physicochemical and immunological studies of thermally induced conformational changes in protein antigens of mycobacterium bovis strain, BCG"],"dc:type":["Doctoral Thesis"],"dc:type.qualificationlevel":["Doctoral"],"dc:type.qualificationname":["PhD"]},"updated_at":"2026-07-22T22:22:38Z"}