{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/14310"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/14310","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Changes in the BCG-Induced T cell response over the first year of life","abstract":"Bacille Calmette-Guerin (BCG), the only currently available tuberculosis vaccine, is the most widely administered vaccine in the Expanded Programme on Immunisation (EPI). Despite this, many gaps in our knowledge of BCG-induced T cell responses exist. The primary objective of this study was to comprehensively delineate T cell immunity induced by BCG vaccination of newborns and to longitudinally assess BCG-specific T cell responses over the first year of life.","abstract_html":"Bacille Calmette-Guerin (BCG), the only currently available tuberculosis vaccine, is the most widely administered vaccine in the Expanded Programme on Immunisation (EPI). Despite this, many gaps in our knowledge of BCG-induced T cell responses exist. The primary objective of this study was to comprehensively delineate T cell immunity induced by BCG vaccination of newborns and to longitudinally assess BCG-specific T cell responses over the first year of life.","abstract_has_math":false,"creators":["Soares, Andreia"],"institution":"Department of Paediatrics and Child Health","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Hanekom, Willem A"],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011","date_published":"2011","updated_at":"2026-07-22T22:22:49Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/14310","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Hanekom, Willem A"]},{"key":"dc:creator","label":"Author","values":["Soares, Andreia"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2015-10-25T17:04:34Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2015-10-25T17:04:34Z"]},{"key":"dc:date.issued","label":"Date","values":["2011"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Paediatrics and Child Health"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Doctoral Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["PhD"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/14310"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Includes bibliographical references (leaves 190-238)."]},{"key":"dc:description.abstract","label":"Abstract","values":["Bacille Calmette-Guerin (BCG), the only currently available tuberculosis vaccine, is the most widely administered vaccine in the Expanded Programme on Immunisation (EPI). Despite this, many gaps in our knowledge of BCG-induced T cell responses exist. The primary objective of this study was to comprehensively delineate T cell immunity induced by BCG vaccination of newborns and to longitudinally assess BCG-specific T cell responses over the first year of life."]},{"key":"dc:title","label":"Title","values":["Changes in the BCG-Induced T cell response over the first year of life"]}]}],"canonical_facts":{"dc:contributor.advisor":["Hanekom, Willem A"],"dc:creator":["Soares, Andreia"],"dc:date.accessioned":["2015-10-25T17:04:34Z"],"dc:date.available":["2015-10-25T17:04:34Z"],"dc:date.issued":["2011"],"dc:description":["Includes bibliographical references (leaves 190-238)."],"dc:description.abstract":["Bacille Calmette-Guerin (BCG), the only currently available tuberculosis vaccine, is the most widely administered vaccine in the Expanded Programme on Immunisation (EPI). Despite this, many gaps in our knowledge of BCG-induced T cell responses exist. The primary objective of this study was to comprehensively delineate T cell immunity induced by BCG vaccination of newborns and to longitudinally assess BCG-specific T cell responses over the first year of life."],"dc:identifier.uri":["http://hdl.handle.net/11427/14310"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Paediatrics and Child Health"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["Changes in the BCG-Induced T cell response over the first year of life"],"dc:type":["Doctoral Thesis"],"dc:type.qualificationlevel":["Doctoral"],"dc:type.qualificationname":["PhD"]},"updated_at":"2026-07-22T22:22:49Z"}