Simultaneous clustering with mixtures of factor analysers

This work details the method of Simultaneous Model-based Clustering. It also presents an extension to this method by reformulating it as a model with a mixture of factor analysers. This allows for the technique, known as Simultaneous Model-Based Clustering with a Mixture of Factor Analysers, to be able to cluster high dimensional gene-expression data. A new table of allowable and non-allowable models is formulated, along with a parameter estimation scheme for one such allowable model. Several numerical procedures are tested and various datasets, both real and generated, are clustered. The results of clustering the Iris data find a 3 component VEV model to have the lowest misclassification rate with comparable BIC values to the best scoring model. The clustering of Genetic data was less successful, where the 2-component model could successfully uncover the healthy tissue, but partitioned the cancerous tissue in half.

Grantor dc:publisher.institution

Department of Medicine

Year dc:date.issued

2013

Author dc:creator

• O'Donnell, Warwick

Advisor dc:contributor.advisor

• Lesosky, Maia

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/13972

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/13972