{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/13771"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/13771","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Validation of the CAT rapid: a smartphone screening tool for HIV-associated neurocognitive disorders in South Africa","abstract":"Existing screening tools are not suitable for the detection of HIV-associated neurocognitive disorders (HAND) in South Africa. Study 1 of the current thesis aimed to establish construct validity of a new screening tool, the Cognitive Assessment Tool-Rapid(CAT-Rapid), in a sample of cognitively healthy South African undergraduates (n = 122).Study 2 investigated the tool¡¯s diagnostic validity in a sample of HIV-positive adult South Africans (n = 89). In Study 1 and Study 2, correlational analyses characterizing the associations between CAT-Rapid subtests and analogous standardized neuropsychological tests sought to establish construct validity. In Study 2, ROC curves, and estimates of sensitivity and specificity values, characterized the CAT-Rapid¡¯s diagnostic validity. Results from Study 1 demonstrated adequate construct validity for the CAT-Rapid in the cognitively healthy sample. Results from Study 2 did not demonstrate construct validity of the tool in the clinical sample. Regarding diagnostic properties, at the recommended cut off score ¡Ü 10, the CAT-Rapid did not demonstrate optimal sensitivity and specificity in the detection of HAND. Future research should investigate how the CAT-Rapid compares to paper-and-pencil screening tests that have demonstrated promising results in studies emerging from the global north.","abstract_html":"Existing screening tools are not suitable for the detection of HIV-associated neurocognitive disorders (HAND) in South Africa. Study 1 of the current thesis aimed to establish construct validity of a new screening tool, the Cognitive Assessment Tool-Rapid(CAT-Rapid), in a sample of cognitively healthy South African undergraduates (n = 122).Study 2 investigated the tool¡¯s diagnostic validity in a sample of HIV-positive adult South Africans (n = 89). In Study 1 and Study 2, correlational analyses characterizing the associations between CAT-Rapid subtests and analogous standardized neuropsychological tests sought to establish construct validity. In Study 2, ROC curves, and estimates of sensitivity and specificity values, characterized the CAT-Rapid¡¯s diagnostic validity. Results from Study 1 demonstrated adequate construct validity for the CAT-Rapid in the cognitively healthy sample. Results from Study 2 did not demonstrate construct validity of the tool in the clinical sample. Regarding diagnostic properties, at the recommended cut off score ¡Ü 10, the CAT-Rapid did not demonstrate optimal sensitivity and specificity in the detection of HAND. Future research should investigate how the CAT-Rapid compares to paper-and-pencil screening tests that have demonstrated promising results in studies emerging from the global north.","abstract_has_math":false,"creators":["Witten, Jade Abigail"],"institution":"Department of Psychology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Thomas, Kevin","Joska, John"],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015","date_published":"2015","updated_at":"2026-07-22T22:23:07Z","subjects":[],"languages":["Eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/13771","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Thomas, Kevin","Joska, John"]},{"key":"dc:creator","label":"Author","values":["Witten, Jade Abigail"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2015-08-15T05:33:40Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2015-08-15T05:33:40Z"]},{"key":"dc:date.issued","label":"Date","values":["2015"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Psychology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MA"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["Eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/13771"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Existing screening tools are not suitable for the detection of HIV-associated neurocognitive disorders (HAND) in South Africa. Study 1 of the current thesis aimed to establish construct validity of a new screening tool, the Cognitive Assessment Tool-Rapid(CAT-Rapid), in a sample of cognitively healthy South African undergraduates (n = 122).Study 2 investigated the tool¡¯s diagnostic validity in a sample of HIV-positive adult South Africans (n = 89). In Study 1 and Study 2, correlational analyses characterizing the associations between CAT-Rapid subtests and analogous standardized neuropsychological tests sought to establish construct validity. In Study 2, ROC curves, and estimates of sensitivity and specificity values, characterized the CAT-Rapid¡¯s diagnostic validity. Results from Study 1 demonstrated adequate construct validity for the CAT-Rapid in the cognitively healthy sample. Results from Study 2 did not demonstrate construct validity of the tool in the clinical sample. Regarding diagnostic properties, at the recommended cut off score ¡Ü 10, the CAT-Rapid did not demonstrate optimal sensitivity and specificity in the detection of HAND. Future research should investigate how the CAT-Rapid compares to paper-and-pencil screening tests that have demonstrated promising results in studies emerging from the global north."]},{"key":"dc:title","label":"Title","values":["Validation of the CAT rapid: a smartphone screening tool for HIV-associated neurocognitive disorders in South Africa"]}]}],"canonical_facts":{"dc:contributor.advisor":["Thomas, Kevin","Joska, John"],"dc:creator":["Witten, Jade Abigail"],"dc:date.accessioned":["2015-08-15T05:33:40Z"],"dc:date.available":["2015-08-15T05:33:40Z"],"dc:date.issued":["2015"],"dc:description.abstract":["Existing screening tools are not suitable for the detection of HIV-associated neurocognitive disorders (HAND) in South Africa. Study 1 of the current thesis aimed to establish construct validity of a new screening tool, the Cognitive Assessment Tool-Rapid(CAT-Rapid), in a sample of cognitively healthy South African undergraduates (n = 122).Study 2 investigated the tool¡¯s diagnostic validity in a sample of HIV-positive adult South Africans (n = 89). In Study 1 and Study 2, correlational analyses characterizing the associations between CAT-Rapid subtests and analogous standardized neuropsychological tests sought to establish construct validity. In Study 2, ROC curves, and estimates of sensitivity and specificity values, characterized the CAT-Rapid¡¯s diagnostic validity. Results from Study 1 demonstrated adequate construct validity for the CAT-Rapid in the cognitively healthy sample. Results from Study 2 did not demonstrate construct validity of the tool in the clinical sample. Regarding diagnostic properties, at the recommended cut off score ¡Ü 10, the CAT-Rapid did not demonstrate optimal sensitivity and specificity in the detection of HAND. Future research should investigate how the CAT-Rapid compares to paper-and-pencil screening tests that have demonstrated promising results in studies emerging from the global north."],"dc:identifier.uri":["http://hdl.handle.net/11427/13771"],"dc:language.iso":["Eng"],"dc:publisher.department":["Department of Psychology"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["Validation of the CAT rapid: a smartphone screening tool for HIV-associated neurocognitive disorders in South Africa"],"dc:type":["Master Thesis"],"dc:type.qualificationlevel":["Masters"],"dc:type.qualificationname":["MA"]},"updated_at":"2026-07-22T22:23:07Z"}