{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/13520"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/13520","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"The separation of diastereoisomers by gas-liquid chromatography","abstract":"The preparation and the gas chromatographic behaviour of several series of diastereoisomeric compounds is described. The series are the following: (1) Alkyl lactates, {2) Afkyl á-alkanoyloxypropionates, (3) Dialkyl esters of 2,3-butanediol, (4) Di-(haloacetic) esters of 2 1 3-butanediol and (5) á,â-Diols. Chromatography was performed at various temperatures and a variety of stationary phases was used. Capillary columns were used for chromatography of series 1 and 2 whereas packed columns were used for series 3 to 5. It was found that for all of the above series nearly all of th compounds could be separated into diastereoisomers. The separability was found to be a function of the chemical structure of the compounds, of the polarity of the stationary phases and of the temperature at which chromatography was performed.","abstract_html":"The preparation and the gas chromatographic behaviour of several series of diastereoisomeric compounds is described. The series are the following: (1) Alkyl lactates, {2) Afkyl á-alkanoyloxypropionates, (3) Dialkyl esters of 2,3-butanediol, (4) Di-(haloacetic) esters of 2 1 3-butanediol and (5) á,â-Diols. Chromatography was performed at various temperatures and a variety of stationary phases was used. Capillary columns were used for chromatography of series 1 and 2 whereas packed columns were used for series 3 to 5. It was found that for all of the above series nearly all of th compounds could be separated into diastereoisomers. The separability was found to be a function of the chemical structure of the compounds, of the polarity of the stationary phases and of the temperature at which chromatography was performed.","abstract_has_math":false,"creators":["Nurok, David"],"institution":"Department of Chemistry","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Stephen, A M"],"committee_chairs":[],"committee_members":[],"year":1966,"date_issued":"1966","date_published":"1966","updated_at":"2026-07-22T22:22:57Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/13520","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Stephen, A M"]},{"key":"dc:creator","label":"Author","values":["Nurok, David"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2015-07-14T09:02:43Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2015-07-14T09:02:43Z"]},{"key":"dc:date.issued","label":"Date","values":["1966"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Chemistry"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Doctoral Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["PhD"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/13520"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The preparation and the gas chromatographic behaviour of several series of diastereoisomeric compounds is described. The series are the following: (1) Alkyl lactates, {2) Afkyl á-alkanoyloxypropionates, (3) Dialkyl esters of 2,3-butanediol, (4) Di-(haloacetic) esters of 2 1 3-butanediol and (5) á,â-Diols. Chromatography was performed at various temperatures and a variety of stationary phases was used. Capillary columns were used for chromatography of series 1 and 2 whereas packed columns were used for series 3 to 5. It was found that for all of the above series nearly all of th compounds could be separated into diastereoisomers. The separability was found to be a function of the chemical structure of the compounds, of the polarity of the stationary phases and of the temperature at which chromatography was performed."]},{"key":"dc:title","label":"Title","values":["The separation of diastereoisomers by gas-liquid chromatography"]}]}],"canonical_facts":{"dc:contributor.advisor":["Stephen, A M"],"dc:creator":["Nurok, David"],"dc:date.accessioned":["2015-07-14T09:02:43Z"],"dc:date.available":["2015-07-14T09:02:43Z"],"dc:date.issued":["1966"],"dc:description.abstract":["The preparation and the gas chromatographic behaviour of several series of diastereoisomeric compounds is described. The series are the following: (1) Alkyl lactates, {2) Afkyl á-alkanoyloxypropionates, (3) Dialkyl esters of 2,3-butanediol, (4) Di-(haloacetic) esters of 2 1 3-butanediol and (5) á,â-Diols. Chromatography was performed at various temperatures and a variety of stationary phases was used. Capillary columns were used for chromatography of series 1 and 2 whereas packed columns were used for series 3 to 5. It was found that for all of the above series nearly all of th compounds could be separated into diastereoisomers. The separability was found to be a function of the chemical structure of the compounds, of the polarity of the stationary phases and of the temperature at which chromatography was performed."],"dc:identifier.uri":["http://hdl.handle.net/11427/13520"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Chemistry"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["The separation of diastereoisomers by gas-liquid chromatography"],"dc:type":["Doctoral Thesis"],"dc:type.qualificationlevel":["Doctoral"],"dc:type.qualificationname":["PhD"]},"updated_at":"2026-07-22T22:22:57Z"}