The effect of dietary lipids on the serum cholesterol concentration of the rat

The effect of different dietary fats on the serum cholesterol concentration has been discussed. In a series of experiments, conditions have been created under which rats can be induced to imitate humans in this respect. Using the rat as an experimental animal, the hypocholesterolaemic property of dietary sunflower seed oil has been investigated by the chemical and physical fractionation of this oil. By feeding the saponifiable and unsaponifiable matter of the sunflower seed oil, it was found that the latter fraction was partly responsible for the serum regulating property of this oil. This finding was confirmed by altering the composition of the unsaponifiable matter by the physical fractionation process of liquid propane segregation. Several fractions of oils with similar fatty acid compositions but differing in both quality and quantity of the unsaponifiable matter were found to have different effects on the serum cholesterol level.

Grantor dc:publisher.institution

Department of Molecular and Cell Biology

Year dc:date.issued

1960

Author dc:creator

• Wilkens, J A

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/13422

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/13422