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(2006) using the ORCA2/PISCES ocean biological model shows that sampling 4 times a year, every 2&#8304; in latitude and every 40&#8304; in longitude reduces the uncertainty of estimating annual CO&#8322; flux estimates such that sampling at a higher frequency does not reduce the total uncertainty in proportion to the increase in sampling effort.","abstract_html":"A model study was undertaken to investigate the optimization of sampling strategies for returning low-uncertainty sea-air CO&amp;#8322; flux measurements in the Southern Ocean. Replicating Lenton et al. 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