FMRI guided DTI at the grey-white matter interface : with application to a connectivity analysis of the default mode network in Urbach-Wiethe disease

The cerebral cortex is composed of a thin layer of Grey Matter (GM), functionally subdivided into discrete regions which are connected in a large scale network via White Matter (WM) tracts. With fMRI (Functional Magnetic Resonance Imaging) it is possible to identify cortical regions involved in specific tasks, and with DTI (Diffusion Tensor Imaging) the structural connections between these areas can be mapped. The aim of this thesis is to to identify and track only those WM tracts entering and leaving a GM Region Of Interest (ROI) defined by fMRI.

Grantor dc:publisher.institution

Division of Biomedical Engineering

Year dc:date.issued

2011

Author dc:creator

• Baasch, Roland

Advisors dc:contributor.advisor

• Spottiswoode, Bruce Shawn
• Morgan, Barak Eli

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/12246

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/12246