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Department of Chemistry
Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
Abstract
dc:description.abstractThe question of whether or not replacing the 7-chloro group in the 4-aminoquinoline moiety with an electron withdrawing and hydrophilic substituent results in retention of antiplasmodial activity in the 4-aminoquinoline class of compounds was investigated...
Degree
thesis:*- Grantor dc:publisher.institution
- Department of Chemistry
- Year dc:date.issued
- 2010
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Nsumiwa, Samkele
- Advisors dc:contributor.advisor
-
- Egan, Timothy J
- Chibale, Kelly
Rights
- Language dc:language.iso
- eng
Identifiers
dc:identifier.*- Handle dc:identifier.uri
- http://hdl.handle.net/11427/12176
- OAI identifier oai:identifier
- oai:open.uct.ac.za:11427/12176