Fluorescent ajoenes as a mechanistic probe for cancer

This thesis describes the development and synthesis of several novel ajoene mimics. The first of which, (E/Z)-1,8-(Bis-p-methoxyphenyl)-2,3,7-trithia-octa-4-ene 7-oxide 17, was developed as a continuation of SAR studies performed by our group, involved the placing p-methoxyphenly groups on the termini of the ajoene pharmacophore.

Grantor dc:publisher.institution

Department of Chemistry

Year dc:date.issued

2010

Author dc:creator

• Cotton, Jonathan

Advisors dc:contributor.advisor

• Hunter, Roger
• Caira, Mino R
• Parker, Iqbal

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/12175

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/12175