{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/11369"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/11369","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Completion of isoniazid preventive therapy and factors associated with non-completion in an antiretroviral therapy-naive HIV-infected cohort in Cape Town by Tolu Oni.","abstract":"TB incidence in South Africa remains high, despite high rates of successful treatment suggesting ongoing transmission and a large reservoir of latently infected persons. Isoniazid preventive therapy (IPT) is recommended as preventive therapy in HIV-infected persons. However, implementation has been slow, impeded by barriers and challenges including the fear of non-adherence. A protocol was therefore written to conduct a study to measure IPT completion rates and evaluate predictors of non-completion of a six-month IPT course in Khayelitsha, an informal township in Cape Town. Prior to data analysis, a structured literature review was conducted to assess available evidence particularly from high-burden settings on IPT completion rates and factors associated with loss to follow up.","abstract_html":"TB incidence in South Africa remains high, despite high rates of successful treatment suggesting ongoing transmission and a large reservoir of latently infected persons. Isoniazid preventive therapy (IPT) is recommended as preventive therapy in HIV-infected persons. However, implementation has been slow, impeded by barriers and challenges including the fear of non-adherence. A protocol was therefore written to conduct a study to measure IPT completion rates and evaluate predictors of non-completion of a six-month IPT course in Khayelitsha, an informal township in Cape Town. Prior to data analysis, a structured literature review was conducted to assess available evidence particularly from high-burden settings on IPT completion rates and factors associated with loss to follow up.","abstract_has_math":false,"creators":["Oni, Tolu"],"institution":"Department of Public Health and Family Medicine","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Coetzee, David"],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012","date_published":"2012","updated_at":"2026-07-22T22:23:18Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/11369","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Coetzee, David"]},{"key":"dc:creator","label":"Author","values":["Oni, Tolu"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2015-01-05T07:00:20Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2015-01-05T07:00:20Z"]},{"key":"dc:date.issued","label":"Date","values":["2012"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Public Health and Family Medicine"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MPhil"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/11369"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["includes bibliographic references."]},{"key":"dc:description.abstract","label":"Abstract","values":["TB incidence in South Africa remains high, despite high rates of successful treatment suggesting ongoing transmission and a large reservoir of latently infected persons. Isoniazid preventive therapy (IPT) is recommended as preventive therapy in HIV-infected persons. However, implementation has been slow, impeded by barriers and challenges including the fear of non-adherence. A protocol was therefore written to conduct a study to measure IPT completion rates and evaluate predictors of non-completion of a six-month IPT course in Khayelitsha, an informal township in Cape Town. 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