The development of penguinpox virus (PEPV) as a vaccine vector : transfer vector construction and rescue of virus growth in rabbit kidney cells (RK-13) by vaccinia virus K1

Of the many vaccine trials which have taken place, the most promising results have been obtained from the recent phase 3 clinical trial which tested the ability of a dual protein and Canarypox virus recombinant to protect humans against HIV-1 infections. Because poxviruses are being developed as vaccine vectors against a number of diseases, it is important to continue the search for novel poxvirus vectors, in particular, those that do not cross-neutralize one another. This thesis describes the preliminary work performed on the development of Penguinpox virus (PEPV) as a vaccine vector.

Grantor dc:publisher.institution

Division of Virology

Year dc:date.issued

2010

Author dc:creator

• Hu, Nai-Chung

Advisors dc:contributor.advisor

• Williamson, Anna-Lise
• Douglass, Nicola

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/10687

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/10687