{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/10491"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/10491","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Active shape model segmentation of Brain structures in MR images of subjects with fetal alcohol spectrum disorder","abstract":"Fetal Alcohol Spectrum Disorder (FASD) is the most common form of preventable mental retardation worldwide. This condition affects children whose mothers excessively consume alcohol whilst pregnant. FASD can be identified by physical and mental defects, such as stunted growth, facial deformities, cognitive impairment, and behavioural abnormalities. Magnetic Resonance Imaging provides a non-invasive means to study the neural correlates of FASD. One such approach aims to detect brain abnormalities through an assessment of volume and shape of sub-cortical structures on high-resolution MR images.","abstract_html":"Fetal Alcohol Spectrum Disorder (FASD) is the most common form of preventable mental retardation worldwide. This condition affects children whose mothers excessively consume alcohol whilst pregnant. FASD can be identified by physical and mental defects, such as stunted growth, facial deformities, cognitive impairment, and behavioural abnormalities. Magnetic Resonance Imaging provides a non-invasive means to study the neural correlates of FASD. One such approach aims to detect brain abnormalities through an assessment of volume and shape of sub-cortical structures on high-resolution MR images.","abstract_has_math":false,"creators":["Eicher, Anton"],"institution":"Department of Computer Science","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Marais, Patrick","Meintjes, Ernesta"],"committee_chairs":[],"committee_members":[],"year":2010,"date_issued":"2010","date_published":"2010","updated_at":"2026-07-22T22:23:00Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/10491","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Marais, Patrick","Meintjes, Ernesta"]},{"key":"dc:creator","label":"Author","values":["Eicher, Anton"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-12-29T05:04:45Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-12-29T05:04:45Z"]},{"key":"dc:date.issued","label":"Date","values":["2010"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Computer Science"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Master Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["MSc"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/10491"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Includes abstract.","Includes bibiographical references (leaves 102-105)."]},{"key":"dc:description.abstract","label":"Abstract","values":["Fetal Alcohol Spectrum Disorder (FASD) is the most common form of preventable mental retardation worldwide. 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