Elucidation of bipolar disorder : a convergent approach using genetics and imaging

The aims were to determine whether variants, within ten selected candidate genes, have an association with BPD and whether any relationship exists between these variants and brain imaging volumes in subjects with BPD. The objectives were to i) select a list of BPD candidate genes, ii) identify a cohort of individuals from the BPD registry, iii) genotype the candidate genes using a polymerase chain reaction (PCR) based technology, iv) analyse the genotyping data with the appropriate statistical methods, and v) obtain brain imaging data and perform the appropriate statistical analysis.

Grantor dc:publisher.institution

Division of Human Genetics

Year dc:date.issued

2011

Author dc:creator

• Dalvie, Shareefa

Advisor dc:contributor.advisor

• Ramesar, Rajkumar S

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/10371

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/10371