Physicochemical studies of the inclusion of selected agrochemicals in cyclodextrins

Pesticides frequently display adverse properties such as low aqueous solubility, low stability, and high toxicity that limit their applications and render them environmentally hazardous. The possibility of improving these physical properties was attempted by complexing four pesticides with native and derivatised cyclodextrins (CDs). The pesticides studied included: the phenylurea herbicide, cycluron; an organochlorine insecticide, endosulfan; an organophosphorus insecticide, fenitrothion; and the chloroacetanilide herbicide, acetochlor. A study of CD complexation with these pesticides in solution as well as in the solid state was undertaken. A further set of experiments was conducted, whereby the thermal stabilities of three isostructural inclusion complexes were evaluated using thermogravimetric analysis.

Grantor dc:publisher.institution

Department of Chemistry

Year dc:date.issued

2011

Author dc:creator

• Cruickshank, Dyanne Louise

Advisors dc:contributor.advisor

• Caira, Mino R
• Bourne, Susan A

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/10318

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/10318