Engineering the Plasmon Resonance of Gold Nanoshells for Biological Applications

Within this research I have investigated the effect of pH and the ratio of gold to silica colloids on the formation of nanoshell precursor seed particles thereby leading to the optimization of the process by which gold nanoshells are formed. With a focus on nanoshells for the thermal ablation of cancer cells, 104.5 nm core shell particles having a peak resonance at 940 nm were formed. The study also presents two new methods by which ‘textured’ nanoshells may be formed for use in applications such as substrates for Surface Enhanced Raman Spectroscopy. The thesis has also investigated the effect of temperature on the surface morphology of the gold nanoshells. Investigations in this respect have led to the finding that the formation of nanoshells at an elevated temperature allows for the generation of nanoshells having a smooth surface morphology, irrespective of the shell thickness.

Name dc:type.qualificationname

MPhil

Level dc:type.qualificationlevel

masters

Grantor dc:publisher.institution

University of Cambridge

Year dc:date.issued

2010

Author dc:creator

• Taha, Nesrine Nagui

• nanoshells
• Spectroscopy
• Gold nanoshells
• multifunctional nanoparticles
• GBMF
• Glioblastoma multiform
• seed nanoparticle formation
• plasmon resonance
• detailed gold nanoshell formation protocol

Licence

• https://apollo8-f-pro.lib.cam.ac.uk/bitstreams/4a7da81a-8912-480d-ac13-fab08087f738/download
• https://www.rioxx.net/licenses/all-rights-reserved/

Language dc:language

en

DOI dc:identifier.doi

https://doi.org/10.17863/CAM.64837

OAI identifier oai:identifier

oai:www.repository.cam.ac.uk:1810/317723