Subclinical atherosclerosis is an important area of research to evaluate stroke risk and predict localization of plaque. The current methods for detecting atherosclerosis risk are insufficient because it is based on The Framingham Risk Score and carotid intima media thickness, therefore an engineering detection model based on quantifiable data is needed. Laminar and turbulent flow, dictated by Reynolds number and relative roughness, was modeled through the carotid artery bifurcation to compare shear stress and shear rate. Computer-aided design and fluid flow software were used to model hemodynamics through the carotid artery. Data from the model was derived from governing equations programmed in COMSOL for both laminar and turbulent flow. A carotid artery model is accurate enough to describe how relative roughness, flow profiles, and shear rate can be a good prediction of subclinical atherosclerosis.
","abstract_html":"<p>Subclinical atherosclerosis is an important area of research to evaluate stroke risk and predict localization of plaque. The current methods for detecting atherosclerosis risk are insufficient because it is based on The Framingham Risk Score and carotid intima media thickness, therefore an engineering detection model based on quantifiable data is needed. Laminar and turbulent flow, dictated by Reynolds number and relative roughness, was modeled through the carotid artery bifurcation to compare shear stress and shear rate. Computer-aided design and fluid flow software were used to model hemodynamics through the carotid artery. Data from the model was derived from governing equations programmed in COMSOL for both laminar and turbulent flow. A carotid artery model is accurate enough to describe how relative roughness, flow profiles, and shear rate can be a good prediction of subclinical atherosclerosis.</p>","abstract_has_math":false,"creators":["Peressini, Marisa"],"institution":null,"degree_name":"MS in Engineering - Biochemical Engineering","degree_level":null,"degree_discipline":"Biomedical and General Engineering","degree_department":null,"school":null,"contributors":["Michael Whitt"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018-06-01T07:00:00Z","date_published":"2018-06-01T07:00:00Z","updated_at":"2026-07-24T01:32:08Z","subjects":["fluid dynamics","COMSOL","flow profiles","shear stress","relative roughness","Biomechanics and Biotransport"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["10.15368/theses.2018.99"],"render_values":[{"text":"10.15368/theses.2018.99","href":"https://doi.org/10.15368/theses.2018.99","code":true}]}]},"links":{"outbound_url":"https://digitalcommons.calpoly.edu/theses/1876","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Michael Whitt"]},{"key":"dc:creator","label":"Author","values":["Peressini, Marisa"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2018-07-18T07:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biomedical and General Engineering"]},{"key":"thesis:degree_name","label":"Degree Name","values":["MS in Engineering - Biochemical Engineering"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["fluid dynamics","COMSOL","flow profiles","shear stress","relative roughness","Biomechanics and Biotransport"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://digitalcommons.calpoly.edu/theses/1876","10.15368/theses.2018.99"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Subclinical atherosclerosis is an important area of research to evaluate stroke risk and predict localization of plaque. The current methods for detecting atherosclerosis risk are insufficient because it is based on The Framingham Risk Score and carotid intima media thickness, therefore an engineering detection model based on quantifiable data is needed. Laminar and turbulent flow, dictated by Reynolds number and relative roughness, was modeled through the carotid artery bifurcation to compare shear stress and shear rate. Computer-aided design and fluid flow software were used to model hemodynamics through the carotid artery. Data from the model was derived from governing equations programmed in COMSOL for both laminar and turbulent flow. A carotid artery model is accurate enough to describe how relative roughness, flow profiles, and shear rate can be a good prediction of subclinical atherosclerosis.
"]},{"key":"dc:title","label":"Title","values":["Detection Method of Subclinical Atherosclerosis of the Carotid Artery with a Hemodynamics Modeling Approach"]}]}],"canonical_facts":{"dc:contributor":["Michael Whitt"],"dc:creator":["Peressini, Marisa"],"dc:date.available":["2018-07-18T07:00:00Z"],"dc:description.abstract":["Subclinical atherosclerosis is an important area of research to evaluate stroke risk and predict localization of plaque. The current methods for detecting atherosclerosis risk are insufficient because it is based on The Framingham Risk Score and carotid intima media thickness, therefore an engineering detection model based on quantifiable data is needed. Laminar and turbulent flow, dictated by Reynolds number and relative roughness, was modeled through the carotid artery bifurcation to compare shear stress and shear rate. Computer-aided design and fluid flow software were used to model hemodynamics through the carotid artery. Data from the model was derived from governing equations programmed in COMSOL for both laminar and turbulent flow. A carotid artery model is accurate enough to describe how relative roughness, flow profiles, and shear rate can be a good prediction of subclinical atherosclerosis.
"],"dc:identifier":["https://digitalcommons.calpoly.edu/theses/1876","10.15368/theses.2018.99"],"dc:subject":["fluid dynamics","COMSOL","flow profiles","shear stress","relative roughness","Biomechanics and Biotransport"],"dc:title":["Detection Method of Subclinical Atherosclerosis of the Carotid Artery with a Hemodynamics Modeling Approach"],"thesis:degree_discipline":["Biomedical and General Engineering"],"thesis:degree_name":["MS in Engineering - Biochemical Engineering"]},"updated_at":"2026-07-24T01:32:08Z"}