Abstract
dc:description.abstractWe employed the reservoir-wave approach to analyze high-fidelity pulmonary arterial (PA) pressure and Doppler flow velocity in 11 patients with varying cardiac diseases. Our specific objectives were to (1) to characterize PA wave pattern and (2) evaluate right ventricular (RV) performance. Wave pressure was partitioned into its forward and backward components. Among patients with lower PA pressures, pressure-decreasing and flow-increasing reflected waves that assist RV ejection were detected. Among the more pulmonary hypertensive patients, pressure-increasing and flow-decreasing reflected waves that impede RV ejection were detected. The four patients with the highest PA pressures showed an early systolic deceleration in flow, which was found to coincide with reflected pressure-increasing, flow-decreasing waves. Wave work done by the RV increased with PA pressure, but expressed as a fraction of total RV work, did not change. The reservoir-wave approach may prove to be a valuable tool to characterize PA-RV interaction and evaluate RV performance.
Degree
thesis:*- Name thesis:degree_name
- Master of Science (MSc)
- Discipline thesis:degree_discipline
- Cardiovascular & Respiratory Sciences
- Grantor dc:publisher.institution
- Graduate Studies
- Year dc:date.issued
- 2016
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Ghimire, Anukul
- Advisors dc:contributor.advisor
-
- Tyberg, John
- Fine, Nowell
- Committee members dc:contributor.committeemember
-
- Belenkie, Israel
- Grant, Andrew
Subjects
dc:subject × 2Rights
dc:rights- Statement dc:rights
-
- University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
- Language dc:language.iso
- eng
Identifiers
dc:identifier.*- OAI identifier oai:identifier
- oai:ucalgary.scholaris.ca:11023/3027