Studio di un modello di correlazione tra la fluttuazione del tenore di metalli pesanti e di altri fattori ambientali e la salute umana in Sardegna
type: CreativeWork
description: Since the first half of the 20th century, the incidence of Multiple Sclerosis (MS), Type 1 Diabetes (T1D) and Autism Spectrum Disorders (ASDs) has increased in Sardinia. T1D results from autoimmune destruction of insulin, producing beta cells of the pancreas; MS is a chronic disease of the central nervous system, causing neurological affliction; Autism is defined as a complex developmental disability that generally appears during the first three years of life. Concerning MS and T1D, Sardinia island has one of the highest incidence rate in the world. In this island, there is the presence of phenotypes of these diseases, due to the homogeneous genetic background of the local population. Indeed, Sardinia population is a genetic isolate. The genetic background by itself does not explain such increasing incidence. T1D and MS increase with latitude, but Sardinia is an exception. Furthermore, mining exploitation was one of the most important economic activities in Sardinia during the past centuries and a lot of data are today available for the researchers. For this reasons Sardinia is an ideal setting to study a possible correlation between environmental factors and the diseases above, because of sardinian people genetic background and environmental peculiarities of the island. A set of environmental data and the frequency data of MS, T1D and ASD were investigated to evaluate the correlation between environmental factors and the frequency of these diseases. In particular, among the environmental factors, geochemical data are included in the Geochemical Database of the Department of Civil, Environmental Engineering and Architecture (DICAAR) of the Cagliari University. This Database is populated by thousands of data concerning soils, rocks and stream sediments. A stream-sediment-type sampling, which is widely used for mineral prospecting, has the advantage of effectively representing the overall geochemical print of a wide portion of territory such as a stream basin. Environ…
abstract: Since the first half of the 20th century, the incidence of Multiple Sclerosis (MS), Type 1 Diabetes (T1D) and Autism Spectrum Disorders (ASDs) has increased in Sardinia. T1D results from autoimmune destruction of insulin, producing beta cells of the pancreas; MS is a chronic disease of the central nervous system, causing neurological affliction; Autism is defined as a complex developmental disability that generally appears during the first three years of life. Concerning MS and T1D, Sardinia island has one of the highest incidence rate in the world. In this island, there is the presence of phenotypes of these diseases, due to the homogeneous genetic background of the local population. Indeed, Sardinia population is a genetic isolate. The genetic background by itself does not explain such increasing incidence. T1D and MS increase with latitude, but Sardinia is an exception. Furthermore, mining exploitation was one of the most important economic activities in Sardinia during the past centuries and a lot of data are today available for the researchers. For this reasons Sardinia is an ideal setting to study a possible correlation between environmental factors and the diseases above, because of sardinian people genetic background and environmental peculiarities of the island. A set of environmental data and the frequency data of MS, T1D and ASD were investigated to evaluate the correlation between environmental factors and the frequency of these diseases. In particular, among the environmental factors, geochemical data are included in the Geochemical Database of the Department of Civil, Environmental Engineering and Architecture (DICAAR) of the Cagliari University. This Database is populated by thousands of data concerning soils, rocks and stream sediments. A stream-sediment-type sampling, which is widely used for mineral prospecting, has the advantage of effectively representing the overall geochemical print of a wide portion of territory such as a stream basin. Environ…
author: SANNA, ALESSANDRO
language: ita
keywords: economic geology, geologia medica, giacimentologia, medical geology, Settore BIO/13 - Biologia Applicata
date published: 2016-03-10
date modified: 2026-07-24T01:30:12Z
provider: Università di Cagliari
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Università degli Studi di Cagliari

PropertyValue
property ID: Handle
value: http://hdl.handle.net/11584/266896